34552-04-0

Basic information

• Product Name: 3,3-DIMETHYL-1-PYRIDIN-2-YLBUTAN-2-ONE
• Synonyms: 3,3-DIMETHYL-1-PYRIDIN-2-YLBUTAN-2-ONE;2-BUTANONE,3,3-DIMETHYL-1-(2-PYRIDINYL)
• CAS NO: 34552-04-0
• Molecular Formula: C11H15NO
• Molecular Weight: 177.24
• Mol File: 34552-04-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 253.4°Cat760mmHg
• Flash Point: 113.6°C
• Appearance: /
• Density: 0.991g/cm³
• Vapor Pressure: 0.0183mmHg at 25°C
• Refractive Index: 1.498
• PKA: 4.61±0.12(Predicted)
• CAS DataBase Reference: 3,3-DIMETHYL-1-PYRIDIN-2-YLBUTAN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-DIMETHYL-1-PYRIDIN-2-YLBUTAN-2-ONE(34552-04-0)
• EPA Substance Registry System: 3,3-DIMETHYL-1-PYRIDIN-2-YLBUTAN-2-ONE(34552-04-0)

Safety Data

• Hazard Codes: Xn:Harmful
• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 34552-04-0(Hazardous Substances Data)

Usage

General Description

3,3-DIMETHYL-1-PYRIDIN-2-YLBUTAN-2-ONE is a chemical compound with the molecular formula C11H15NO. It is classified as a pyridine derivative and contains a ketone functional group. 3,3-DIMETHYL-1-PYRIDIN-2-YLBUTAN-2-ONE is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. It may also be utilized in the production of flavoring agents, fragrances, and other consumer products. 3,3-DIMETHYL-1-PYRIDIN-2-YLBUTAN-2-ONE is not known to be naturally occurring and is primarily produced through synthetic chemical processes. Its precise properties and applications may vary depending on the specific manufacturing method and intended use.

InChI:InChI=1/C11H15NO/c1-11(2,3)10(13)8-9-6-4-5-7-12-9/h4-7H,8H2,1-3H3

Upstream product

• 109-04-6 2-bromo-pyridine 
• 75-97-8 3,3-dimethyl-butan-2-one 
• 109-06-8 α-picoline 
• 630-18-2 tert-butyl isocyanide 

Relevant articles and documents

Tautomer-selective derivatives of enolate, ketone and enaminone by addition reaction of picolyl-type anions with nitriles

We describe an efficient for the synthesis of compounds of tautomeric β-pyridyl/quinolyl-enol, -ketone, -enaminone, which were finally characterized by standard methods like NMR, IR or SCXRD. The addition reaction of lithiated intermediates of picoline, 2-ethylpyridine and 2-methylquinoline, respectively, with nitriles followed by acid hydrolysis afforded the corresponding tautomeric compounds of enol, ketone and emaminone. Interestingly, treatment of 2-methylpyridine or 2-ethylpyridine with nitriles, respectively, yielded mostly β-pyridyl ketone and enol tautomers without enaminones, while 2-methylquinoline with nitriles gave β-quinolyl ketone and enaminone tautomers without enols. The reaction of 2-benzylpyridine with nitriles was not available under the same conditions.

THE RELATIVE REACTIVITY OF SUBSTRATE IN SRN1 REACTIONS

The factors affecting the relative reactivity of aryl halides in SRN1 aromatic nucleophilic substitutions are analyzed and compared.Competition experiments of pairs of substrates, in photostimulated reaction with pinacolone enolate ion in liqui