345909-35-5

Basic information

• Product Name: 4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID, HYDRATE, 98
• Synonyms: 2-Carboxy-4-hydroxyquinoline hydrate, 4-Hydroxyquinaldic acid hydrate, Kynurenic acid hydrate;4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID, HYDRATE, 98
• CAS NO: 345909-35-5
• Molecular Formula: C10H7NO3.H2O
• Molecular Weight: 207.184
• EINECS: 207-751-5
• Mol File: 345909-35-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 275°C
• Boiling Point: 358.4°Cat760mmHg
• Flash Point: 170.5°C
• Appearance: Yellow to brown/Crystalline Powder
• Density: g/cm³
• Vapor Pressure: 9.28E-06mmHg at 25°C
• Water Solubility: Soluble in hot ethanol and water. Insoluble in ether.
• Merck: 14,5327
• BRN: 147451
• CAS DataBase Reference: 4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID, HYDRATE, 98(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID, HYDRATE, 98(345909-35-5)
• EPA Substance Registry System: 4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID, HYDRATE, 98(345909-35-5)

Safety Data

• RTECS: VB2080000
• Hazardous Substances Data: 345909-35-5(Hazardous Substances Data)

Usage

Description

4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID, HYDRATE, 98 is a yellow to brown crystalline powder that serves as a broad-spectrum excitatory amino acid antagonist. It is used as an intermediate in synthetic chemistry and possesses antiexcitotoxic and anticonvulsant properties, making it a potential candidate for the treatment of certain neurobiological disorders.

Uses

Used in Pharmaceutical Industry:
4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID, HYDRATE, 98 is used as an intermediate in synthetic chemistry for the development of various pharmaceutical compounds. Its antiexcitotoxic and anticonvulsant properties make it a valuable component in the formulation of drugs targeting neurobiological disorders.
Used in Neurobiological Disorder Therapy:
4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID, HYDRATE, 98 is used as a therapeutic agent for the treatment of certain neurobiological disorders. Its ability to act as an excitatory amino acid antagonist helps in mitigating the effects of these conditions by reducing excitotoxicity and preventing seizures.
Used in Research and Development:
4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID, HYDRATE, 98 is also utilized in research and development for the study of its potential applications in various fields, including pharmaceuticals, neuroscience, and synthetic chemistry. Its unique properties and versatility make it an interesting subject for further investigation and potential development of new therapeutic agents.

InChI:InChI=1/C10H7NO3/c12-9-5-8(10(13)14)11-7-4-2-1-3-6(7)9/h1-5H,(H,11,12)(H,13,14)/p-1