34723-82-5

Basic information

• Product Name: 2-(BROMOMETHYL)TETRAHYDRO-2 H-PYRAN
• Synonyms: TETRAHYDRO-2 H-PYRAN-2-METHYL BROMIDE;2-(BROMOMETHYL)TETRAHYDRO-2 H-PYRAN;Pyran, 2-(bromomethyl)tetrahydro-;2H-Pyran, 2-(bromomethyl)tetrahydro-;2-(Bromomethyl)tetrahydro-2H-pyran ,98%;2-(bromomethyl)oxane;2-(bromomethyl)tetrahydropyran;2-(Bromomethyl)tetrahydro-2H-pyran 98%
• CAS NO: 34723-82-5
• Molecular Formula: C₆H₁₁BrO
• Molecular Weight: 179.05
• Product Categories: Building Blocks;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyrans
• Mol File: 34723-82-5.mol
• Article Data: 1

Chemical Properties

• Melting Point: −59-−58 °C(lit.)
• Boiling Point: 153 °C(lit.)
• Flash Point: 149 °F
• Appearance: colorless to yellow liquid
• Density: 1.397 g/mL at 25 °C(lit.)
• Vapor Pressure: 4.36mmHg at 25°C
• Refractive Index: n20/D 1.489(lit.)
• CAS DataBase Reference: 2-(BROMOMETHYL)TETRAHYDRO-2 H-PYRAN(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(BROMOMETHYL)TETRAHYDRO-2 H-PYRAN(34723-82-5)
• EPA Substance Registry System: 2-(BROMOMETHYL)TETRAHYDRO-2 H-PYRAN(34723-82-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 34723-82-5(Hazardous Substances Data)

Usage

Description

2-(Bromomethyl)tetrahydro-2H-pyran is a colorless to yellow liquid that has been investigated for its cross-coupling reaction with potassium heteroaryltrifluoroborates. 2-(BROMOMETHYL)TETRAHYDRO-2 H-PYRAN is known for its role in the preparation of tellurated heterocycles, which are important in various chemical and pharmaceutical applications.

Uses

Used in Chemical Synthesis:
2-(Bromomethyl)tetrahydro-2H-pyran is used as a key intermediate in the synthesis of tellurated heterocycles, such as 2-[(2-thienyltelluro)methyl]tetrahydrofuran and [(2-thienyltelluro)methyl]tetrahydro-2H-pyran. These heterocycles are valuable for their unique chemical properties and potential applications in various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-(Bromomethyl)tetrahydro-2H-pyran is used as a building block for the development of new drugs. Its ability to form tellurated heterocycles makes it a promising candidate for the creation of novel therapeutic agents with potential applications in treating various diseases.
Used in Material Science:
2-(Bromomethyl)tetrahydro-2H-pyran is also utilized in the field of material science for the development of new materials with unique properties. The tellurated heterocycles derived from this compound can be used to create advanced materials with improved performance in areas such as electronics, optics, and energy storage.

InChI:InChI=1/C6H11BrO/c7-5-6-3-1-2-4-8-6/h6H,1-5H2

Upstream product

• 100-72-1 Tetrahydropyran-2-methanol 

Downstream Products

• 111293-46-0 2-(oxan-2-ylmethyl)-2,3-dihydro-1H-isoindole-1,3-dione 
• 821-41-0 5-Hexen-1-ol 
• 594815-23-3 3-(4-chloro-phenyl)-2-phenyl-4-(tetrahydro-pyran-2-ylmethyl)-4H-furo[3,2-b]pyrrole-5-carboxylic acid ethyl ester 
• 909872-86-2 C₂₈H₃₇N₃O₆S 

Relevant articles and documents

A new simple and industrial process for bromination of alcohols

Alcohols treated with thionylchloride, followed by chlorine/bromine exchange using gaseous hydrobromic acid and thermal decomposition in the presence of a tertiary amine give the corresponding brominated compounds. The process is regio/stereo selective.