34737-89-8

Basic information

• Product Name: 1-BENZYL-3-METHYL-4-PIPERIDONE
• Synonyms: TIMTEC-BB SBB001741;4-PIPERIDINONE, 3-METHYL-1-(PHENYLMETHYL)-;1-BENZYL-3-METHYL-4-PIPERIDONE;1-BENZYL-3-METHYLPIPERIDIN-4-ONE;N-BeNzyl-3-methyl-4-piperidoNe;3-Methyl-1-(phenylmethyl)-4-piperidinone;1-Benzyl-3-methyl-4-piperidone,99%;1-Benzyl-3-methyl-4-piperidinone
• CAS NO: 34737-89-8
• Molecular Formula: C₁₃H₁₇NO
• Molecular Weight: 203.28
• EINECS: 252-176-5
• Product Categories: pharmacetical;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 34737-89-8.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 99°C/0.05mmHg(lit.)
• Flash Point: 134.9°C
• Appearance: Clear slightly yellow to yellow/Liquid
• Density: 1.0156 (rough estimate)
• Vapor Pressure: 0.498mmHg at 25°C
• Refractive Index: 1.5315-1.5335
• Storage Temp.: Refrigerator
• Solubility: Chloroform, Methanol
• PKA: 7.11±0.40(Predicted)
• CAS DataBase Reference: 1-BENZYL-3-METHYL-4-PIPERIDONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BENZYL-3-METHYL-4-PIPERIDONE(34737-89-8)
• EPA Substance Registry System: 1-BENZYL-3-METHYL-4-PIPERIDONE(34737-89-8)

Safety Data

• Hazard Codes: C
• Statements: 34-22
• Safety Statements: 45-36/37/39-26
• RIDADR: 2735
• HazardClass: 8
• PackingGroup: Ⅲ
• Hazardous Substances Data: 34737-89-8(Hazardous Substances Data)

Usage

Description

1-Benzyl-3-methyl-4-piperidone is a piperidine derivative characterized by its clear slightly yellow to yellow liquid appearance. It is a chemical compound with a specific molecular structure that plays a significant role in the pharmaceutical industry.

Uses

1-Benzyl-3-methyl-4-piperidone is used as an intermediate in the pharmaceutical industry for the preparation of Fentanyl (F274990) analogs. These analogs exhibit potent analgesic activity, making them valuable in the development of pain-relieving medications.
Used in Pharmaceutical Industry:
1-Benzyl-3-methyl-4-piperidone is used as a key component in the synthesis of Fentanyl analogs for their analgesic properties. 1-Benzyl-3-methyl-4-piperidone contributes to the development of effective pain management solutions, particularly for severe and chronic pain conditions.

InChI:InChI=1/C5H4N2O/c8-4-5-3-6-1-2-7-5/h1-4H

Upstream product

• 3612-20-2 1-phenylmethyl-4-piperidone 
• 74-88-4 methyl iodide 
• 7006-50-0 1-benzyl-N-methylpiperidin-4-amine 
• 7087-68-5 N-ethyl-N,N-diisopropylamine 
• 103-80-0 phenylacetyl chloride 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 127956-04-1 ethyl 1-benzyl-3-methyl-4-oxopiperidine-3-carboxylate 
• 1285576-65-9 C₁₄H₂₁NO₃ 
• 1589566-76-6 2-methyl-3-[(2-iodoethyl)(phenylmethyl)amino]-propanoic acid 
• 41276-30-6 C₉H₁₄O₃NC₆H₅ 

Downstream Products

• 147292-25-9 (+/-)-1-benzyl-t-4-cyano-r-3-methyl-N-phenyl-4-piperidinamine 
• 147292-25-9 (+/-)-1-benzyl-c-4-cyano-r-3-methyl-N-phenyl-4-piperidinamine 
• 58328-99-7 [1-Benzyl-3-methyl-piperidin-(4E)-ylidene]-phenyl-amine 
• 58329-00-3 (+/-)-cis-1-benzyl-3-methyl-N-phenylpiperidinamine 
• 58329-00-3 (+/-)-trans-1-benzyl-3-methyl-N-phenylpiperidinamine 
• 58328-99-7 1-benzyl-3-methyl-4-phenyliminopiperidine 
• 58329-00-3 1-benzyl-3-methyl-N-phenyl-4-piperidinamine 
• 5773-58-0 3-methyl-4-piperidone 
• 157048-15-2 2-phenylmethyl-8a-methyl-1,3,4,7,8,8a-hexahydro-6(2H)-isoquinolinone 
• 176796-70-6 (R)-1-benzyl-3-methyl-3-(3-oxo-butyl)-piperidin-4-one 
• 176796-98-8 (S)-1-Benzyl-3-methyl-3-(3-oxo-butyl)-piperidin-4-one 
• 107418-97-3 ethyl (2E)-(1-benzyl-3-methylpiperidin-4-ylidene)acetate 
• 168888-69-5 1-benzyl-3-methyl-1,2,5,6-tetrahydro-4-pyridineacetic acid ethyl ester 
• 1006587-14-9 1-benzyl-N-cyclopropyl-3-methylpiperidin-4-amine 

Relevant articles and documents

INTERMEDIATES FOR OPTICALLY ACTIVE PIPERIDINE DERIVATIVES AND PREPARATION METHODS THEREOF

A preparation method according to the present invention makes it possible to industrially produce large amounts of highly pure optically active tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate in high yield by use of commercially available reagents and solvents. In addition, the use of novel intermediates according to the present invention makes it possible to produce highly pure optically active tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate in high yield.

NOVEL TETRAHYDROPYRIDOPYRIMIDINES AND TETRAHYDROPYRIDOPYRIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION

The invention provides novel compounds having the general formula (I): wherein R1, R2, R3, Q, U,W, Z, X and Y are as described herein, compositions including the compounds and methods of using the compounds. These compounds are HbsAg inhibitors and are useful as medicaments for the treatment or prophylaxis of HBV infection.

COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF

Provided herein are compounds and methods of synthesis thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, psychiatric disorders, neuromuscular disorders, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds provided herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.