34750-63-5 Usage
General Description
1,6-Dihydro-6-oxo-2-(3-pyridinyl)-5-pyrimidinecarboxylic acid ethyl ester, also known as baricitinib, is a chemical compound with potential therapeutic applications. It belongs to the class of pyrimidine carboxylic acid derivatives and is commonly used as a selective inhibitor of Janus kinases, particularly JAK1 and JAK2. This inhibition can modulate immune system responses and potentially be beneficial in the treatment of autoimmune diseases such as rheumatoid arthritis. Additionally, baricitinib has shown promise in the treatment of COVID-19, as it inhibits cytokine release and reduces inflammation. As such, it is being studied for its potential as a treatment for a variety of inflammatory and autoimmune conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 34750-63-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,4,7,5 and 0 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 34750-63:
(7*3)+(6*4)+(5*7)+(4*5)+(3*0)+(2*6)+(1*3)=115
115 % 10 = 5
So 34750-63-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H11N3O3/c1-2-18-12(17)9-7-14-10(15-11(9)16)8-4-3-5-13-6-8/h3-7H,2H2,1H3,(H,14,15,16)
34750-63-5Relevant articles and documents
PYRIMIDINE COMPOUNDS AS DELTA OPIOID RECEPTOR MODULATORS
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Page/Page column 44-45, (2011/05/08)
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows:wherein R1, R2, R3, and L, A, and Ra are defined herein.