34984-16-2

Basic information

• Product Name: 2,6-PyridinediMethanaMine
• Synonyms: 2,6-PyridinediMethanaMine;2,6-Bis(aminomethyl)pyridine;2,6-Bis(aminomethyl)pyridine, min. 95%;Pyridine-2,6-diyldimethanamine
• CAS NO: 34984-16-2
• Molecular Formula: C₇H₁₁N₃
• Molecular Weight: 137.18234
• Product Categories: Achiral Nitrogen;Py-N
• Mol File: 34984-16-2.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 257.5±30.0 °C(Predicted)
• Appearance: low melting yellow/solid
• Density: 1.118±0.06 g/cm3(Predicted)
• PKA: 8.99±0.39(Predicted)
• Sensitive: air sensitive
• CAS DataBase Reference: 2,6-PyridinediMethanaMine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-PyridinediMethanaMine(34984-16-2)
• EPA Substance Registry System: 2,6-PyridinediMethanaMine(34984-16-2)

Safety Data

• Hazardous Substances Data: 34984-16-2(Hazardous Substances Data)

Usage

General Description

2,6-PyridinediMethanaMine, also known as 2,6-Pyridinedicarboxaldehyde or 2,6-lutidine, is a chemical compound with the molecular formula C7H7N. It is a heterocyclic amine that is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. It is a colorless liquid with a strong odor and is highly flammable. 2,6-PyridinediMethanaMine is also used as an intermediate in the production of dyes, pigments, and surfactants. It is important to handle this chemical with care and follow proper safety precautions due to its flammability and toxic nature.

Upstream product

• 2893-33-6 pyridine-2,6-dinitrile 
• 2851-68-5 pyridine-2,6-dicarbaldehyde dioxime 
• 4663-97-2 pyridine-2,6-dicarboxylic acid diamide 
• 1195-59-1 2.6-bis(hydroxymethyl)pyridine 
• 136918-14-4 phthalimide 
• 67455-81-6 2,6-bis(phthalimidomethyl)pyridine 
• 1972-28-7 diethylazodicarboxylate 
• 200489-04-9 2,6-bis(azidomethyl)pyridine 
• 7703-74-4 2,6-bis-(bromomethyl)pyridine 
• 38881-63-9 2,6-bis-(aminomethyl)pyridine trihydrochloride 
• 3099-28-3 2,6-bis(chloromethyl)pyridine 
• 499-83-2 Pyridine-2,6-dicarboxylic acid 
• 5453-67-8 2,6-bis(methoxycarbonyl)pyridine 

Downstream Products

• 67455-83-8 2,2'-(pyridine-2,6-diyldimethyldiimino-dimethyl)-bis-phenol 
• 80197-28-0 2,6-Bis(3,4,5-trimethoxybenzoylaminomethyl)pyridine 
• 112633-27-9 2,6-bis<(p-tosylamino)methyl>pyridine 
• 67478-28-8 2,6-bis-(benzoylamino-methyl)-pyridine 
• 98572-18-0 3,11-ditosyl-3,11,17,18-tetraazatricyclo<11.3.1^5,9>octadeca-1(17),5(18),6,8,13,15-hexaene 
• 125682-93-1 2,6-bis<methyl>pyridine 
• 125683-02-5 2,6-bis<methyl>-N-tosylamino>methyl>pyridine 
• 125682-94-2 2,6-bis<-N-tosylamino>methyl>pyridine 
• 125683-03-6 2,6-bis<pyridin-2-yl>methyl>-N-tosylamino>methyl>pyridine 
• 125682-95-3 3,9,17,23-tetratosyl-3,9,17,23,29,30-hexaaza-6,20-dioxatricyclo<23.3.1.1^11,15>triaconta-1(29),11(30),12,14,25,27-hexaene 
• 125683-06-9 3,11,19,27-tetratosyl-3,11,19,27,33,34,35,36-octaazapentacyclo<27.3.1.1^5,9.1^13,17.1^21,25>hexatriaconta-1(33),5(34),6,8,13(35),14,16,21(36),22,24,29,31-dodecaene 
• 125683-04-7 3,6,9,17,25-pentatosyl-3,6,9,17,25,31,32,33-octaazatetracyclo<25.3.1.1^11,15.1^19,23>tritriaconta-1(31),11(32),12,14,19(33),20,22,27,29-nonaene 
• 125683-05-8 3,7,11,19,27-pentatosyl-3,7,11,19,27,33,34,35-octaazatetracyclo<27.3.1.1^13,17.1^21,25>pentatriaconta-1(33),13(34),14,16,21(35),22,24,29,31-nonaene 
• 100919-57-1 3,9,12,15,21-pentatosyl-3,9,12,15,,21,27-hexaaza-6,18-dioxabicyclo<21.3.1>heptaicosa-1(27),23,25-triene 

Relevant articles and documents

Formation of very stable and selective Cu(II) complexes with a non-macrocyclic ligand: Can basicity rival pre-organization?

The synthesis of ligand L based on a 2,6-bis[(N,N-bis(methylene phosphonic acid)aminomethyl] pyridine scaffold is described. Potentiometry combined with UV-Vis absorption spectrophotometric titrations were used to determine the protonation constants of the ligand and the stability constants of its corresponding Cu(II), Ni(II), Zn(II) and Ga(III) cations (0.1 M NaClO 4, 25.0 °C). The physico-chemical approach revealed very large stability constants for Cu(II) complexation (logKCuL = 22.71(7)) reflected in a very high pCuII value of ～ 15.5 (pH = 7.4, [L]tot = 10-5 M, [Cu]tot = 10-6 M), close to those measured for the strong methylphosphonate functionalized cyclen chelators. Based on a literature survey, a correlation is proposed between the pK values of branched polyamine ligands and their stability constants for Cu(II) complexation, allowing for an estimation of the latter on the basis of the protonation constants of L. Ligand L was also shown to be very selective towards Cu(II) compared to the other cations studied (ΔlogK > 4). UV-Vis spectroscopy and kinetic measurements indicated that the formation of the cupric complexes with L is very fast, which, in combination with all other properties, makes it an excellent non-cyclic target for Cu(II) radiopharmaceutical within the frame of 64Cu positron emission tomography imaging and radiotherapy. The Royal Society of Chemistry 2010.

Assisted π-stacking: a strong synergy between weak interactions

Synergy between a pair of weak non-covalent interactions can predispose a molecular self-assembly towards a specific pathway. We report assisted π-stacking, a synergy between aromatic π-stacking and n → π* interactions that exhibits an unprecedented strength and thermal stability. Natural bond orbital analysis reveals the non-additive nature of the interaction.

XYLYLENEDIAMINE COMPOSITION AND METHOD OF PRODUCING POLYAMIDE RESIN

The invention provides [1] a xylylenediamine composition containing a xylylenediamine and a pyridine compound (A) having at least one substituent which contains an amino group, wherein the amount of the pyridine compound (A) is from 0.001 to 0.1 parts by mass per 100 parts by mass of the xylylenediamine; and [2] a method of producing a polyamide resin having a step in which a pyridine compound (A) having at least one substituent which contains an amino group, a diamine including a xylylenediamine (but excluding diamines which correspond with the pyridine compound (A)) and a dicarboxylic acid are introduced into a reaction system and subjected to a polycondensation reaction, wherein the amount added of the pyridine compound (A) is from 0.001 to 0.1 parts by mass per 100 parts by mass of the xylylenediamine.