350691-08-6

Basic information

• Product Name: 2-Naphthalenecarboxaldehyde, 3,4-dihydro-1-(2-methylphenyl)-
• CAS NO: 350691-08-6
• Molecular Formula: C18H16O
• Molecular Weight: 248.324
• Mol File: 350691-08-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Naphthalenecarboxaldehyde, 3,4-dihydro-1-(2-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Naphthalenecarboxaldehyde, 3,4-dihydro-1-(2-methylphenyl)-(350691-08-6)
• EPA Substance Registry System: 2-Naphthalenecarboxaldehyde, 3,4-dihydro-1-(2-methylphenyl)-(350691-08-6)

Safety Data

• Hazardous Substances Data: 350691-08-6(Hazardous Substances Data)

Upstream product

• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 95-46-5 2-methylphenyl bromide 
• 16419-60-6 2-Methylphenylboronic acid 
• 117582-62-4 1-bromo-2-formyl-3,4-dihydronaphthalene 
• 3262-03-1 1-chloro-2-formyl-3,4-dihydronaphthalene 

Downstream Products

• 883221-17-8 [1-(o-tolyl)-3,4-dihydronaphthalen-2-yl]methyl acetate 
• 195-19-7 benzo[c]phenathrene 

Relevant articles and documents

Methodology for the synthesis of 1,2-disubstituted arylnaphthalenes from α-tetralones

α-Tetralones were initially converted into 1-bromo- dihydronaphthalene-2-carbaldehydes and 1-bromo-naphthalene-2-carbaldehydes. These precursors were then subjected to Suzuki coupling reactions to afford 1,2-disubstituted aryldihydronaphthalenes and 1,2-disubstituted arylnaphthalenes, respectively. The former products were oxidized with DDQ to give 1,2-disubstituted arylnaphthalenes.

Palladium-catalyzed C-C bond formation from β-chloroacroleins in aqueous media

The Suzuki coupling of several β-chloroacroleins with arylboronic acids was successfully performed with good yields under mild conditions (3 h at 45°C) in aqueous media without any organic co-solvent.