351446-99-6Relevant articles and documents
Non-peptide αvβ3 antagonists. Part 7: 3-Substituted tetrahydro-[1,8]naphthyridine derivatives
Wang, Jiabing,Breslin, Michael J.,Coleman, Paul J.,Duggan, Mark E.,Hunt, Cecilia A.,Hutchinson, John H.,Leu, Chih-Tai,Rodan, Sevgi B.,Rodan, Gideon A.,Duong, Le T.,Hartman, George D.
, p. 1049 - 1052 (2007/10/03)
A series of 3-substituted tetrahydro-[1,8]naphthyridine containing αvβ3 antagonists was prepared. A comparison of their in vitro IC50 values to the electron properties of the 3-substituents revealed a good linear Hammett c