352276-27-8

Basic information

• Product Name: 2-Butanone, 1-iodo-4-phenyl-
• Synonyms: 2-Butanone,1-iodo-4-phenyl;1-iodo-4-phenyl-2-butanone
• CAS NO: 352276-27-8
• Molecular Formula: C10H11IO
• Molecular Weight: 274.101
• Mol File: 352276-27-8.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-Butanone, 1-iodo-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butanone, 1-iodo-4-phenyl-(352276-27-8)
• EPA Substance Registry System: 2-Butanone, 1-iodo-4-phenyl-(352276-27-8)

Safety Data

• Hazardous Substances Data: 352276-27-8(Hazardous Substances Data)

Upstream product

• 31984-10-8 1-bromo-4-phenylbutan-2-one 
• 2344-70-9 1-phenyl-3-butanol 
• 2550-26-7 4-Phenyl-2-butanone 
• 645-45-4 hydrocinnamic acid chloride 
• 20845-80-1 1-chloro-4-phenylbutan-2-one 

Downstream Products

• 40601-45-4 diethyl (2-oxo-4-phenylbutyl)phosphonate 
• 62510-08-1 1,5-diphenyl-1-penten-3-one 
• 62731-45-7 1-hydroxy-1,5-diphenyl-pentan-3-one 
• 41162-19-0 dimethyl(2-oxo-4-phenylbutyl)phosphonate 
• 155206-00-1 bimatoprost 
• 38315-47-8 (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-((S)-(E)-3-hydroxy-5-phenylpent-1-enyl)-cyclopentyl]hept-5-enoic acid methyl ester 
• 477884-78-9 C₄₄H₈₂O₅Si₃ 
• 130209-82-4 latanoprost 
• 82102-19-0 2-amino-4-phenylbutylphosphonic acid 

Relevant articles and documents

Visible-Light-Triggered Iodinations Facilitated by Weak Electrostatic Interaction of N-Heterocyclic Carbenes

N-heterocyclic carbenes (NHCs) are well-known as ligands and organocatalysts, but there is no recognition for their catalytic role as a stabilizer through electrostatic interaction rather than electron donation. By utilizing the electrostatic interaction, we herein describe the success of a visible-light-triggered radical-radical cross-coupling of N-alkenoxypyridinium salts and NaI, giving a variety of α-iodo ketones. Computational studies characterize the stabilization role of NHCs.

A Facile and Efficient Synthesis of (15R)-Latanoprost from Chiral Precursor Corey Lactone Diol

An efficient asymmetric synthetic route for the synthesis of anti-glaucoma agent, (15R)-latanoprost using Corey lactone diol as chiral substrate under Swern oxidation, allylic reduction and Wittig reaction conditions has been developed. In this method, reduction of keto and alkene functional groups has been achieved in a single step using low cost catalyst NiCl2/NaBH4 in methanol. This new synthetic protocol is a good alternative for the synthesis of latanoprost with high stereo selectivity and improved yield. [Figure not available: see fulltext.]

Synthesis of (±)-bimatoprost

A general synthetic approach has been developed for the synthesis of a key intermediate (6) that can be elaborated into several ophthalmic prostaglandins and their derivatives. Using these strategy, we have obtained (±)-bimatoprost (1) and its analog, (±)-homobimatoprost (5). Copyright Taylor & Francis Group, LLC.