352359-22-9 Usage
General Description
1-(tert-butoxycarbonyl)-6-chloro-1H-indol-2-ylboronic acid is a chemical compound that contains a boronic acid functional group and a tert-butoxycarbonyl protecting group. It is commonly used in organic synthesis and medicinal chemistry as a reagent for the formation of carbon-carbon and carbon-heteroatom bonds. The presence of the chloro and indole groups also makes it useful for the synthesis of biologically active compounds, including pharmaceuticals and agrochemicals. 1-(TERT-BUTOXYCARBONYL)-6-CHLORO-1H-INDOL-2-YLBORONIC ACID is often used in the preparation of complex molecules for various research and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 352359-22-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,2,3,5 and 9 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 352359-22:
(8*3)+(7*5)+(6*2)+(5*3)+(4*5)+(3*9)+(2*2)+(1*2)=139
139 % 10 = 9
So 352359-22-9 is a valid CAS Registry Number.
InChI:InChI=1/C13H15BClNO4/c1-13(2,3)20-12(17)16-10-7-9(15)5-4-8(10)6-11(16)14(18)19/h4-7,18-19H,1-3H3
352359-22-9Relevant articles and documents
A kind of aldosterone synthase modulators method for the preparation of intermediates
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, (2017/02/28)
The invention discloses a method for preparing an aldosterone synthase conditioning agent intermediate. The method comprises the following steps: implementing reaction on a reaction substrate under Boc protection with hydrogen chloride and ethanol for acetal protection, directly heating to remove Boc protection without separation, implementing N-methylation reaction so as to obtain an N-methylation product, and directly removing acetal protection without separation, thereby obtaining a target product. The method is high in route reaction conversion rate and high in product purity, the product quality can be effectively ensured, and workshop production can be achieved.
SUBSTITUTED PYRAZOLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE
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Page/Page column 34, (2008/06/13)
The present invention relates to substituted pyrazoles, compositions containing such compounds and methods of treatment. The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes
