35249-62-8

Basic information

• Product Name: 3-(2-BROMO-4,5-DIMETHOXYPHENYL)PROPANENITRILE
• Synonyms: 3-(2-BROMO-4,5-DIMETHOXYPHENYL)PROPANENITRILE
• CAS NO: 35249-62-8
• Molecular Formula: C₁₁H₁₂BrNO₂
• Molecular Weight: 270.12248
• EINECS: 609-105-1
• Mol File: 35249-62-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 379.4°Cat760mmHg
• Flash Point: 183.3°C
• Appearance: /
• Density: 1.375g/cm³
• Vapor Pressure: 5.87E-06mmHg at 25°C
• Refractive Index: 1.537
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-(2-BROMO-4,5-DIMETHOXYPHENYL)PROPANENITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-BROMO-4,5-DIMETHOXYPHENYL)PROPANENITRILE(35249-62-8)
• EPA Substance Registry System: 3-(2-BROMO-4,5-DIMETHOXYPHENYL)PROPANENITRILE(35249-62-8)

Safety Data

• Hazardous Substances Data: 35249-62-8(Hazardous Substances Data)

Usage

General Description

3-(2-Bromo-4,5-dimethoxyphenyl)propanenitrile is a chemical compound with the molecular formula C11H11BrO2N. It is a nitrile derivative of 2-Bromo-4,5-dimethoxyphenylpropan-1-one, which is used as an intermediate in the production of various pharmaceuticals and organic compounds. 3-(2-BROMO-4,5-DIMETHOXYPHENYL)PROPANENITRILE is commonly used in the synthesis of complex molecules due to its versatile reactivity and stability. It is a white to off-white solid that is sparingly soluble in water but soluble in organic solvents. This chemical is primarily used in research and development and is not widely available for commercial use.

InChI:InChI=1/C11H12BrNO2/c1-14-10-6-8(4-3-5-13)9(12)7-11(10)15-2/h6-7H,3-4H2,1-2H3

Upstream product

• 1208977-77-8 2-bromo-4,5-dimethoxycinnamonitrile 
• 41234-20-2 3-(2-bromo-4,5-dimethoxyphenyl)-2-cyanopropionic acid 
• 49621-56-9 3-(3,4-dimethoxyphenyl)propanenitrile 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 37629-85-9 (2E)-3-(3,4-dimethoxyphenyl)prop-2-enenitrile 
• 2859-78-1 4-Bromoveratrole 
• 53207-00-4 1-bromo-2-(bromomethyl)-4,5-dimethoxybenzene 
• 75-05-8 acetonitrile 
• 93-03-8 (3,4-dimethoxyphenyl)methanol 

Downstream Products

• 84003-65-6 3-(2-bromo-4,5-dihydroxyphenyl)propionitrile 
• 84003-66-7 3,4-bis(benzyloxy)-7-(hydroxymethyl)bicyclo<4.2.0>octa-1,3,5-triene 
• 81615-14-7 3,4-bis(benzyloxy)bicyclo<4.2.0>octa-1,3,5-triene-7-carbonitrile 
• 81615-15-8 3,4-bis(benzyloxy)bicyclo<4.2.0>octa-1,3,5-triene-7-carboxylic acid 
• 81615-17-0 3,4-bis(benzyloxy)bicyclo<4.2.0>octa-1,3,5-triene-7-carboxylic acid chloride 
• 81615-12-5 3-<2-bromo-4,5-bis(benzyloxy)phenyl>propionitrile 
• 84003-88-3 3,4-bis(benzyloxy)-N-methyl-N-(2-oxoethyl)bicyclo<4.2.0>octa-1,3,5-triene-7-carboxamide 
• 84003-85-0 3,4-bis(benzyloxy)-N-(2-hydroxyethyl)-N-methylbicyclo<4.2.0>octa-1,3,5-triene-7-carboxamide 
• 84003-68-9 3,4-bis(benzyloxy)-7-<<2,2-(dimethoxyethyl)amino>methyl>-bicyclo<4.2.0>octa-1,3,5-triene 
• 84003-84-9 3,4-bis(benzyloxy)-N-(2-hydroxyethyl)-N-propylbicyclo<4.2.0>octa-1,3,5-triene-7-carboxamide 
• 84003-76-9 3,4-bis(benzyloxy)-N-(2-oxoethyl)-N-propylbicyclo<4.2.0>octa-1,3,5-triene-7-carboxamide 
• 84003-70-3 3,4-bis(benzyloxy)-7-<<(methoxycarbonyl)(2-oxoethyl)amino>methyl>-bicyclo<4.2.0>octa-1,3,5-triene 
• 84003-74-7 3,4-bis(benzyloxy)-N-(2,2-dimethoxyethyl)-bicyclo<4.2.0>octa-1,3,5-triene-7-carboxamide 
• 84003-89-4 3,4-bis(benzyloxy)-N-benzyl-N-(2-oxoethyl)bicyclo<4.2.0>octa-1,3,5-triene-7-carboxamide 

Relevant articles and documents

PROCESS FOR THE SYNTHESIS OF 3-(2-BROMO-4,5-DIMETHOXYPHENYL)PROPANENITRILE, AND APPLICATION IN THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID

Process for the synthesis of the compound of formula (I): Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof.

PROCESS FOR THE SYNTHESIS OF 3-(2-BROMO-4,5-DIMETHOXYPHENYL)PROPANENITRILE, AND APPLICATION IN THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID

Process for the synthesis of the compound of formula (I): Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof.