35265-04-4

Basic information

• Product Name: 2-[(1-methylpropyl)amino]ethanol
• Synonyms: 2-[(1-methylpropyl)amino]ethanol;2-(sec-Butylamino)ethanol
• CAS NO: 35265-04-4
• Molecular Formula: C₆H₁₅NO
• Molecular Weight: 117.1894
• EINECS: 252-471-9
• Mol File: 35265-04-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 191.4°Cat760mmHg
• Flash Point: 72.1°C
• Appearance: /
• Density: 0.872g/cm³
• Vapor Pressure: 0.138mmHg at 25°C
• Refractive Index: 1.433
• PKA: 10.126[at 20 ℃]
• Water Solubility: 544g/L at 20℃
• CAS DataBase Reference: 2-[(1-methylpropyl)amino]ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(1-methylpropyl)amino]ethanol(35265-04-4)
• EPA Substance Registry System: 2-[(1-methylpropyl)amino]ethanol(35265-04-4)

Safety Data

• Hazardous Substances Data: 35265-04-4(Hazardous Substances Data)

Usage

General Description

2-[(1-methylpropyl)amino]ethanol, also known as buphenine or 2-(1-methylpropylamino)ethanol, is a chemical compound with the formula C7H17NO. It is classified as a secondary amine and an alcohol, and is commonly used as a pharmaceutical intermediate in the synthesis of various drugs. The compound is a clear, colorless liquid with a faint amine odor, and is soluble in water and organic solvents. It is also used as a corrosion inhibitor in metalworking fluids and as an emulsifier and stabilizer in industrial products. Additionally, 2-[(1-methylpropyl)amino]ethanol has potential applications in the formulation of cosmetics and personal care products. It is important to handle and use this chemical with proper safety precautions due to its potential health hazards.

InChI:InChI=1/C6H15NO/c1-3-6(2)7-4-5-8/h6-8H,3-5H2,1-2H3

Upstream product

• 141-43-5 ethanolamine 
• 78-84-2 isobutyraldehyde 
• 17026-89-0 2-methyl-2-ethyl-2,3,4,5-tetrahydroisoxazole 
• 106345-16-8 4-sec-Butyl-1-oxa-4-aza-spiro[4.5]decane 
• 78-93-3 butanone 
• 75-21-8 oxirane 
• 33966-50-6 SEC-BUTYLAMINE 

Downstream Products

• 96063-94-4 Benzilsaeure-<2-(1-methyl-propylamino)-aethylester> 
• 2654-04-8 N-Phenyl-N'-<2-methyl-propyl>-N'-<2-hydroxy-aethyl>-thioharnstoff 

Relevant articles and documents

Process For Preparing Alkylalkanolamines

The present invention relates to a process for preparing alkylalkanolamines, comprising the reaction of a carbonyl-based compound with a hydroxylalkylamine, in the presence of hydrogen and a catalyst.

Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents

This invention relates to 2-arylimino heterocycles, including 2-arylimino-1,3-thiazolidines, 2-arylimino-2,3,4,5-tetrahydro-1,3-thiazines, 2-arylimino-1,3-thiazolidin-4-ones, 2-arylimino-1,3-thiazolidin-5-ones, and 2-arylimino-1,3-oxazolidines, and their use in modulating progesterone receptor mediated processes, and pharmaceutical compositions for use in such therapies.

Reductive Alkylation of β-Alkanolamines with Carbonyl Compounds and Sodium Borohydride

A synthesis of secondary alkylalkanolamines from primary alkanolamines in a rapid process in which overalkylation is virtually suppressed is described.The procedure combines the ease of formation of oxazolidines from alkanolamines with aldehydes or ketones in absolute ethanol and the lability of the newly formed C-O bond toward sodium borohydrode.The entire process is carried out in 15-35 min depending on the carbonyl substrate.