35339-68-5

Basic information

• Product Name: (1alpha,3beta)-cholest-5-ene-1,3-diyl diacetate
• Synonyms: (1alpha,3beta)-cholest-5-ene-1,3-diyl diacetate;Cholest-5-ene-1α,3β-diol diacetate
• CAS NO: 35339-68-5
• Molecular Formula: C₃₁H₅₀O₄
• Molecular Weight: 486.7263
• EINECS: 252-517-8
• Mol File: 35339-68-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 536.1°Cat760mmHg
• Flash Point: 254.4°C
• Appearance: /
• Density: 1.04g/cm³
• CAS DataBase Reference: (1alpha,3beta)-cholest-5-ene-1,3-diyl diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (1alpha,3beta)-cholest-5-ene-1,3-diyl diacetate(35339-68-5)
• EPA Substance Registry System: (1alpha,3beta)-cholest-5-ene-1,3-diyl diacetate(35339-68-5)

Safety Data

• Hazardous Substances Data: 35339-68-5(Hazardous Substances Data)

Usage

Description

(1alpha,3beta)-cholest-5-ene-1,3-diyl diacetate is a chemical compound with the molecular formula C29H46O4. It is a diacetate derivative of cholesterol, which is a type of steroid and a crucial component of cell membranes. (1alpha,3beta)-cholest-5-ene-1,3-diyl diacetate is often used in research as a precursor to synthesize various cholesterol derivatives and as a starting material for the preparation of pharmaceutical drugs. Additionally, it is used in the production of various hormones and vitamin D. Due to its significance in biological processes, (1alpha,3beta)-cholest-5-ene-1,3-diyl diacetate is commonly studied in the field of biochemistry and organic chemistry.

Uses

Used in Pharmaceutical Industry:
(1alpha,3beta)-cholest-5-ene-1,3-diyl diacetate is used as a starting material for the synthesis of various pharmaceutical drugs. Its role in the production of hormones and vitamin D makes it an essential component in the development of medications targeting hormonal imbalances and related health conditions.
Used in Research and Development:
In the field of biochemistry and organic chemistry, (1alpha,3beta)-cholest-5-ene-1,3-diyl diacetate is used as a precursor to synthesize a wide range of cholesterol derivatives. This allows researchers to explore the structure, function, and potential applications of these cholesterol-related compounds, contributing to the advancement of scientific knowledge and the development of new therapeutic agents.

Upstream product

• 26358-75-8 1α,3β-dihydroxycholest-5-ene 
• 108-24-7 acetic anhydride 
• 28893-44-9 1α,2α-epoxycholesta-1,4,6-trien-3-one 
• 80239-44-7 1α-Hydroxy-5-cholesten-3-on 
• 65061-67-8 1α,2α-Epoxy-cholest-5-en-3β-ol 
• 26358-75-8 24-methylenecholest-5-ene-1α,3β-diol 

Downstream Products

• 41461-10-3 1α,3β-diacetoxycholesta-5,7-diene 
• 43217-89-6 1α,3β-dihydroxycholesta-5,7-diene 
• 41294-56-8 1α-hydroxyvitamin D3 
• 77-71-4 5,5-dimethyl-imidazolidine-2,4-dione 

Relevant articles and documents

Synthesis and evaluation of new 6-hydroximinosteroid analogs as cytotoxic agents

Taking into account the structural requirements for cytotoxicity, several new hydroximinosteroid derivatives have been prepared and evaluated for their cytotoxic activity against A-549, H116, PSN1, and T98G cultured tumor cell lines in order to obtain further information on the potential pharmacophoric core of this type of compound. The influence of the oxygenated position in the A ring, the presence of an additional oxygenated position at C-7 and C-16, and a fluorinated position at C-5 were considered in order to study the structure-activity relationships. The results reveal the importance of oxygenated positions in the A ring (e.g., 4,5-epoxide showed an IC50 value against HCT-116 under micromolar level) for an increase in cytotoxic activity in this type of compound. Furthermore, they showed an important selectivity toward colon tumor line (HCT-116).

Sterols in Marine Invertebrates. 49. Isolation and Structure Elucidation of Eight New Polyhydroxylated Sterols from the Soft Coral Sinularia dissecta

A new group of polyhydroxylated sterols - all of them possessing an 11α-hydroxy substituents of potential utility as corticosteroid intermediates - has been isolated from the soft coral Sinularia dissecta.Their general structure was deduced from spectral data (500-MHz and 360-MHz 1H and 13C NMR and MS) and their stereochemistry was determined by correlating the respective spectral data (1H and 13C NMR) with those of synthetic sterols with similar structure and known configuration.

Studies in 1α-hydroxyl derivatives of vitamin D3. I. Syntheses of 1α-hydroxyvitamin D3 and 1α,25-dihydroxyvitamin D3

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