3541-37-5

Basic information

• Product Name: BENZO[B]THIOPHENE-2-CARBOXALDEHYDE
• Synonyms: Benzo[b]thiophene-2-carboxaldehyde, 98%+;2-benzothiophenecarboxaldehyde;BUTTPARK 98\04-19;BENZOTHIOPHENE-2-CARBALDEHYDE;BENZO[B]THIOPHENE-2-CARBALDEHYDE;BENZO[B]THIOPHENE-2-CARBOXALDEHYDE;AKOS BC-0216;2-FORMYLBENZO[B]THIOPHENE
• CAS NO: 3541-37-5
• Molecular Formula: C₉H₆OS
• Molecular Weight: 162.21
• EINECS: -0
• Product Categories: Aldehyde;Benzothiophene;Building Blocks
• Mol File: 3541-37-5.mol
• Article Data: 59

Chemical Properties

• Melting Point: 30-32°C
• Boiling Point: 90°C 0,1mm
• Flash Point: 135-136°C/8mm
• Appearance: /
• Density: 1.3 g/cm³
• Vapor Pressure: 0.000944mmHg at 25°C
• Refractive Index: 1.719
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• Sensitive: Air Sensitive
• BRN: 114170
• CAS DataBase Reference: BENZO[B]THIOPHENE-2-CARBOXALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZO[B]THIOPHENE-2-CARBOXALDEHYDE(3541-37-5)
• EPA Substance Registry System: BENZO[B]THIOPHENE-2-CARBOXALDEHYDE(3541-37-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-24/25-22
• WGK Germany: 3
• Hazardous Substances Data: 3541-37-5(Hazardous Substances Data)

Usage

Description

BENZO[B]THIOPHENE-2-CARBOXALDEHYDE is an organic compound that belongs to the class of heterocyclic compounds, specifically a derivative of benzo[b]thiophene. It is characterized by its white to light brown solid appearance and is known for its unique chemical properties that make it suitable for various applications in different industries.

Uses

Used in Pharmaceutical Industry:
BENZO[B]THIOPHENE-2-CARBOXALDEHYDE is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure allows for the development of new drugs with potential therapeutic applications.
Used in Chemical Synthesis:
BENZO[B]THIOPHENE-2-CARBOXALDEHYDE is used as a key building block in the preparation of various organic compounds, including the corresponding vinyl benzyl ether using Julia olefination. This process is essential for the development of new materials and chemicals with specific properties and applications.
Used in Research and Development:
Due to its unique chemical properties, BENZO[B]THIOPHENE-2-CARBOXALDEHYDE is also used in research and development for the exploration of new chemical reactions and the synthesis of novel compounds with potential applications in various fields, such as materials science, pharmaceuticals, and agrochemicals.

InChI:InChI=1/C9H6OS/c10-6-8-5-7-3-1-2-4-9(7)11-8/h1-6H

Upstream product

• 50779-55-0 benzothiophen-2-yllithium 
• 93-61-8 N-methyl-N-phenylformamide 
• 130966-73-3 1,1-dimethoxy-2-(2-formylthiophenoxy)ethane 
• 68-12-2 N,N-dimethyl-formamide 
• 95-15-8 Benzo[b]thiophene 
• 1195-14-8 2-Methylbenzothiophene 
• 6314-28-9 benzo[b]thiophene-2-carboxylic acid 
• 17890-56-1 benzothiophene-2-methanol 
• 50-00-0 formaldehyd 
• 130966-70-0 1,1-dimethoxy-2-(2-(2-hydroxymethyl)thiophenoxy)ethane 
• 147-93-3 Thiosalicylic acid 
• 67-56-1 methanol 
• 2700-30-3 N,N-diisorpopylformamide 
• 2591-86-8 N-Formylpiperidine 

Downstream Products

• 86213-36-7 (Z)-2-phenyl-3-(2-benzothienyl)acrylonitrile 
• 124112-33-0 (2-benzothienyl)bis(4-dimethylaminophenyl)methane 
• 109256-01-1 (E)-3-(benzo[b]thiophen-2-yl)-1-phenyl-2-propen-1-one 
• 10133-42-3 benzo[b]thiophene-2-carbaldehyde-(2,4-dinitro-phenylhydrazone) 
• 10135-00-9 3-bromobenzo[b]thiophene-2-carbaldehyde 
• 79966-29-3 2-<2-(1-benzothiophen-2-yl-1-hydroxymethyl)phenyl>-4,4-dimethyl-2-oxazoline 
• 81410-09-5 3-thiophen-2-yl)vinyl>-4-phenyl-3-cyclobuten-1,2-dion 
• 158530-79-1 2-((E)-2-Benzenesulfonyl-vinyl)-benzo[b]thiophene 
• 36634-77-2 2-styryl-benzo[b]thiophene 
• 84258-60-6 2-(p-methylstyryl)benzothiophene 
• 84258-59-3 2-(m-methylstyryl)benzothiophene 
• 84322-02-1 2-benzothenylideneaminocyclohexane 
• 17890-56-1 benzothiophene-2-methanol 
• 249762-36-5 (benzo[b]thiophen-2-yl)(5-methoxy-1-phenylsulfonyl-1H-2-indolyl)methanol 

Relevant articles and documents

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Ruthenium-on-Carbon-Catalyzed Facile Solvent-Free Oxidation of Alcohols: Efficient Progress under Solid-Solid (Liquid)-Gas Conditions

A protocol for the ruthenium-on-carbon (Ru/C)-catalyzed solvent-free oxidation of alcohols, which proceeds efficiently under solid-solid (liquid)-gas conditions, was developed. Various primary and secondary alcohols were transformed to corresponding aldehydes and ketones in moderate to excellent isolated yields by simply stirring in the presence of 10% Ru/C under air or oxygen conditions. The solvent-free oxidation reactions proceeded efficiently regardless of the solid or liquid state of the substrates and reagents and could be applied to gram-scale synthesis without loss of the reaction efficiency. Furthermore, the catalytic activity of Ru/C was maintained after five reuse cycles.

Efficient synthesis of acrylates bearing an aryl or heteroaryl moiety: One-pot method from aromatics and heteroaromatics using formylation and the horner-wadsworth-emmons reaction

Acrylates bearing an aryl or heteroaryl moiety were efficiently prepared by a one-pot process employing a sequence of lithiation, formylation and the Horner-Wadsworth-Emmons reaction starting from aromatic and heteroaromatic compounds. This method can efficiently introduce an acrylate moiety into aromatic and heteroaromatic compounds.

Selective Electrochemical Oxygenation of Alkylarenes to Carbonyls

An efficient electrochemical method for benzylic C(sp3)-H bond oxidation has been developed. A variety of methylarenes, methylheteroarenes, and benzylic (hetero)methylenes could be converted into the desired aryl aldehydes and aryl ketones in moderate to excellent yields in an undivided cell, using O2 as the oxygen source and lutidinium perchlorate as an electrolyte. On the basis of cyclic voltammetry studies, 18O labeling experiments, and radical trapping experiments, a possible single-electron transfer mechanism has been proposed for the electrooxidation reaction.