35438-57-4 Usage
General Description
1,5-Dioxepan-2-one, also known as p-dioxanone, is a chemical compound with the molecular formula C5H8O3. It is a cyclic ester commonly used in the production of biodegradable polymers and copolymers. 1,5-Dioxepan-2-one is of interest due to its potential applications in the medical field, particularly in the development of absorbable sutures and drug delivery systems. Its biodegradability and biocompatibility make it a favorable candidate for use in medical devices. Additionally, 1,5-Dioxepan-2-one is being researched for its potential use in tissue engineering and regenerative medicine. As a result, it is an important chemical in the field of polymer chemistry and biomedical engineering.
Check Digit Verification of cas no
The CAS Registry Mumber 35438-57-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,4,3 and 8 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 35438-57:
(7*3)+(6*5)+(5*4)+(4*3)+(3*8)+(2*5)+(1*7)=124
124 % 10 = 4
So 35438-57-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H8O3/c6-5-1-2-7-3-4-8-5/h1-4H2
35438-57-4Relevant articles and documents
Amide prodrug derivatives as protein kinase inhibitors
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Paragraph 0177; 0184-0187, (2019/02/04)
The invention relates to amide prodrug compounds of novel kinase inhibitors. The prodrugs are characterized in that amino of original drugs is subjected to amidation modification, so that bioavailability of the original drugs in vivo is significantly improved. The invention further relates to pharmaceutical composition containing the prodrugs and a method for treating cancer or other cell proliferative abnormal diseases by the prodrugs and the pharmaceutical composition.
A simple and efficient synthesis of 1,4-And 1,5-dioxepan-2-one
Hassannia, Ali,Piercy, Graeme,Merbouh, Nabyl
experimental part, p. 478 - 480 (2010/04/23)
A novel synthesis of 1,4-and 1,5-dioxepan-2-one lactones was achieved through the regioselective oxidation of 3-(2-hydroxyethoxy)propan-1-ol. Under basic conditions, when 3-(2-hydroxyethoxy)propan-1-ol was oxidized using oxoammonium salts, a quantitative
