355137-87-0

Basic information

• Product Name: AC-ALA-AMC
• Synonyms: ACETYL-L-ALANINE 7-AMIDO-4-METHYLCOUMARIN;AC-ALA-AMC;AC-ALANINE-AMC;N-ALPHA-ACETYL-L-ALANINE 7-AMIDO-4-METHYLCOUMARIN
• CAS NO: 355137-87-0
• Molecular Formula: C15H16N2O4
• Molecular Weight: 288.3
• Mol File: 355137-87-0.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: -15°C
• CAS DataBase Reference: AC-ALA-AMC(CAS DataBase Reference)
• NIST Chemistry Reference: AC-ALA-AMC(355137-87-0)
• EPA Substance Registry System: AC-ALA-AMC(355137-87-0)

Safety Data

• Hazardous Substances Data: 355137-87-0(Hazardous Substances Data)

Usage

General Description

AC-ALA-AMC, also known as N-acetyl-Ala-AMC or N-acetyl-L-alanine-7-amido-4-methylcoumarin, is a fluorogenic substrate that is often used in enzymatic assays to detect the activity of proteases such as trypsin and chymotrypsin. It is a synthetic peptide containing the amino acid alanine and a fluorophore (7-amino-4-methylcoumarin) that becomes fluorescent upon cleavage by proteases. The resulting fluorescence can be measured and quantified, providing a sensitive and convenient method for studying protease activity. AC-ALA-AMC is commonly used in research and drug discovery applications to screen for inhibitors of proteases and to study their function in biological systems. Overall, it is a valuable tool for studying proteases, which play crucial roles in various physiological and pathological processes.