3561-68-0

Basic information

• Product Name: 1,3,3-tris(benzenesulfonyl)propylsulfonylbenzene
• CAS NO: 3561-68-0
• Molecular Formula: C₂₇H₂₄O₈S₄
• Molecular Weight: 604.747
• Mol File: 3561-68-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 916°Cat760mmHg
• Flash Point: 600.3°C
• Density: 1.427g/cm³
• CAS DataBase Reference: 1,3,3-tris(benzenesulfonyl)propylsulfonylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,3-tris(benzenesulfonyl)propylsulfonylbenzene(3561-68-0)
• EPA Substance Registry System: 1,3,3-tris(benzenesulfonyl)propylsulfonylbenzene(3561-68-0)

Safety Data

• Hazardous Substances Data: 3561-68-0(Hazardous Substances Data)

Usage

Abbreviation

TPPSB

Chemical class

Sulfone

Molecular weight

584.68 g/mol

Physical state

White to yellow solid

Solubility

Soluble in organic solvents such as ethanol and chloroform

Applications

a. Crosslinking agent in polymer chemistry
b. Coupling reagent in organic synthesis
c. Potential applications in organic electronics

Biological activity

Investigated for anti-cancer properties

Cancer cell inhibition

Shown to inhibit the growth of cancer cells in laboratory experiments

Further research

Needed to fully understand its potential therapeutic applications

Upstream product

• 108-98-5 thiophenol 
• 39082-53-6 1,1-bis(phenylsulfonyl)ethylene 
• 108-94-1 cyclohexanone 
• 590-86-3 isovaleraldehyde 
• 3561-67-9 bis(phenylthio)methane 
• 2394-07-2 1,1-bis(phenylsulphonyl)methyl methyl sulphone 
• 75-09-2 dichloromethane 
• 3406-02-8 bis(phenylsulfonyl)methane 
• 100-46-9 benzylamine 
• 124-30-1 1-aminooctadecane 
• 109-89-7 diethylamine 
• 110-58-7 n-Pentylamine 
• 110-91-8 morpholine 
• 110-89-4 piperidine 

Relevant articles and documents

Organocatalytic addition on l,2-bis(sulfone)vinylenes leading to an unprecedented rearrangement

A study was conducted to demonstrate the use of 1,2-bis(sulfone)vinylenes in enamine catalysis. It was revealed that these sulfones led to a new rearrangement arising from a sulfone shift to the adjacent carbon atom. Investigations also revealed that the use of cheaper (Z)-1,2-bis(sulfone) vinylene lead to full conversion after a short reaction time in dioxane, using H2O as co-catalyst to accelerate the reaction. A careful NMR investigation indicated that the new product was gem-disulfone, which was supported by authentic sample.

THE REACTION BETWEEN PHENYLIODONIUM BIS(PHENYLSULFONYL)METHANIDE AND PYRROLIDINE

The main product from the title reaction is the enamine N--pyrrolidine, 4.Tetrakis(phenylsulfonyl)propane, 3, is a by-product, when dichloromethane is used; it is formed independently from this solvent and bis(phenylsulfonyl)methane in the presence of pyrrolidine.Key words: Phenyliodonium bis(phenylsulfonyl)methanide, N--pyrrolidine, 1,1,3,3-tetrakis(phenylsulfonyl)propane, dichloromethane, pyrrolidine.

REACTIONS OF 1,1-BIS(ARYLSULFONYL)ETHENES WITH NUCLEOPHILIC AND ELECTROPHILIC REAGENTS

The reaction of 1,1-bis(arylsulfonyl)ethenes with nucleophilic reagents (aromatic and heterocyclic thiols, sulfinic acids) leads to the formation of 1,1-bis(arylsulfonyl)-2-aryl(heteryl)-thio(sulfonyl)ethanes.The anions of CH acids (nitromethane, aromatic