35746-43-1

Basic information

• Product Name: 2(3H)-Oxazolone, 3,5-diphenyl-
• CAS NO: 35746-43-1
• Molecular Formula: C15H11NO2
• Molecular Weight: 237.258
• Mol File: 35746-43-1.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2(3H)-Oxazolone, 3,5-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Oxazolone, 3,5-diphenyl-(35746-43-1)
• EPA Substance Registry System: 2(3H)-Oxazolone, 3,5-diphenyl-(35746-43-1)

Safety Data

• Hazardous Substances Data: 35746-43-1(Hazardous Substances Data)

Upstream product

• 5883-81-8 2-anilinoacetophenone 
• 3282-32-4 2-diazo-acetophenone 
• 103-71-9 phenyl isocyanate 
• 61416-35-1 2-anilino-1-phenyl-ethanone; hydrochloride 
• 530-62-1 1,1'-carbonyldiimidazole 
• 75-44-5 phosgene 
• 10562-01-3 1-phenyl-3,3-bis-(phenylamino)prop-2-en-1-one 
• 1011269-13-8 N-phenyl-N-phenylethynylcarbamic acid tert-butyl ester 
• 1259117-83-3 tert-butyl 2,2-dibromovinyl(phenyl)carbamate 
• 98-80-6 phenylboronic acid 

Relevant articles and documents

Palladium-catalyzed intramolecular cyclization of ynamides: Synthesis of 4-halo-oxazolones

A mild and efficient methodology involving Pd(PPh3)4-catalyzed intramolecular cyclization of N-alkynyl alkyloxycarbamates with CuCl2 or CuBr2 for the synthesis of 4-halo-oxazolones was developed. This reaction exhibiting good functional tolerance provided a new, efficient, and rapid synthetic process to 4-halo-oxazolones. The resulting 4-halo-oxazolones can serve as great potential precursors for the 3,4,5-trisubstituted oxazolones via a Pd-catalyzed cross-coupling reaction.

An efficient silver tetrafluoroborate-catalyzed cycloisomerization of ynamides

A silver catalyzed-cycloisomerization of N-Boc protected ynamides has been developed under mild reaction conditions to provide a wide range of oxazol-2(3H)-ones in good to excellent yields. Moreover, the acid-promoted Pictet-Spengler cyclization of oxazol

Reaction of Ynamides with Iminoiodinane-Derived Nitrenes: Formation of Oxazolones and Polyfunctionalized Oxazolidinones

This article describes the reaction of ynamides with metallanitrenes generated in the presence of an iodine(III) oxidant. N-(Boc)-Ynamides are converted to oxazolones via a cyclization reaction. The reaction is mediated by a catalytic dirhodium-bound nitrene species that first behaves as a Lewis acid. The oxazolones can be converted in a one pot manner to functionalized oxazolidinones following a regio- and stereoselective oxyamination reaction with the same nitrene reagent generated in stoichiometric amounts.