35794-11-7 Usage
Description
3,5-Dimethylpiperidine is an organic compound with the molecular formula C7H13N. It is a heterocyclic amine with two methyl groups attached to the 3rd and 5th positions of the piperidine ring. 3,5-Dimethylpiperidine is known for its unique chemical properties and versatile applications in various industries.
Uses
Used in Pharmaceutical Industry:
3,5-Dimethylpiperidine is used as a reactant for the synthesis of various pharmaceutical compounds, including substituted bisphenol A derivatives, which act as β-amyloid peptide aggregation inhibitors. These inhibitors are crucial for the development of drugs targeting neurodegenerative diseases such as Alzheimer's.
Used in Biochemical Research:
In the field of biochemical research, 3,5-Dimethylpiperidine serves as a reactant for the synthesis of MMP-13 selective isonipecotamide α-sulfone hydroxamates. These hydroxamates are essential for studying the role of matrix metalloproteinases in various biological processes and diseases.
Used in Organic Synthesis:
3,5-Dimethylpiperidine is used as a reactant for the synthesis of gem-diamines, which are active organocatalysts for biodiesel production. These organocatalysts play a significant role in the development of sustainable and environmentally friendly fuel alternatives.
Used in Immunology:
In the field of immunology, 3,5-Dimethylpiperidine is used as a reactant for the synthesis of benzimidazole inhibitors of the antigen receptor-mediated NF-κB pathway. These inhibitors are vital for understanding the regulation of immune responses and the development of immunomodulatory drugs.
Used in Coordination Chemistry:
3,5-Dimethylpiperidine also serves as a reactant for Mannich reactions to form Ru(II) complexes. These complexes are of interest in coordination chemistry and have potential applications in catalysis and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 35794-11-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,7,9 and 4 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 35794-11:
(7*3)+(6*5)+(5*7)+(4*9)+(3*4)+(2*1)+(1*1)=137
137 % 10 = 7
So 35794-11-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H15N/c1-6-3-7(2)5-8-4-6/h6-8H,3-5H2,1-2H3/p+1/t6-,7-/m0/s1
35794-11-7Relevant articles and documents
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Windle et al.
, p. 2630,2631 (1969)
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HYDROGENATION PROCESS
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Page/Page column 27-28, (2020/01/24)
A process for the production of heterocyclic quaternary ammonium salts or hydroxides is disclosed. The process comprises a continuous hydrogenation step, in which an unsaturated heterocyclic amine is reacted with hydrogen to form a saturated heterocyclic amine; a first continuous N-alkylation step, in which the saturated heterocyclic amine is alkylated to produce an intermediate saturated heterocyclic amine having an increased degree of substitution compared to the saturated heterocyclic amine; and one or more further N-alkylation steps in which the intermediate saturated heterocyclic amine is N-alkylated to the heterocyclic quaternary ammonium salt or hydroxide. A process of producing a saturated heterocyclic amineis also disclosed. The process comprises reacting an unsaturated heterocyclic amine with hydrogen in a vapour phase reaction at a pressure of not more than 70 bar and a temperature in the range of from 150°C to 350°C. A process of N-alkylating a saturated heterocyclic amine is also disclosed. The process comprises N-alkylating the saturated heterocyclic amine in a vapour phase reaction at a temperature of at least 2°C.
Cobalt-bridged secondary building units in a titanium metal-organic framework catalyze cascade reduction of N-heteroarenes
Feng, Xuanyu,Song, Yang,Chen, Justin S.,Li, Zhe,Chen, Emily Y.,Kaufmann, Michael,Wang, Cheng,Lin, Wenbin
, p. 2193 - 2198 (2019/02/20)
We report here a novel Ti3-BPDC metal-organic framework (MOF) constructed from biphenyl-4,4′-dicarboxylate (BPDC) linkers and Ti3(OH)2 secondary building units (SBUs) with permanent porosity and large 1D channels. Ti-OH groups from neighboring SBUs point toward each other with an O-O distance of 2 ?, and upon deprotonation, act as the first bidentate SBU-based ligands to support CoII-hydride species for effective cascade reduction of N-heteroarenes (such as pyridines and quinolines) via sequential dearomative hydroboration and hydrogenation, affording piperidine and 1,2,3,4-tetrahydroquinoline derivatives with excellent activity (turnover number ~ 1980) and chemoselectivity.