35840-91-6Relevant articles and documents
Construction of azacycles by intramolecular amination of organoboronates and organobis(boronates)
Xu, Peilin,Zhang, Mingkai,Ingoglia, Bryan,Allais, Christophe,Dechert-Schmitt, Anne-Marie R.,Singer, Robert A.,Morken, James P.
, p. 3379 - 3383 (2021/05/10)
Intramolecular amination of organoboronates occurs with a 1,2-metalate shift of an aminoboron ate complex to form azetidines, pyrrolidines, and piperidines. Bis(boronates) undergo site-selective amination to form boronate-containing azacycles. Enantiomerically enriched azacycles are formed with high stereospecificity.
O-benzoylhydroxylamines as alkyl nitrene precursors: Synthesis of saturated N-heterocycles from primary amines
Noda, Hidetoshi,Asada, Yasuko,Shibasaki, Masakatsu
supporting information, p. 8769 - 8773 (2020/10/12)
We introduce O-benzoylhydroxylamines as competent alkyl nitrene precursors. The combination of readily available, stable substrates and a proficient rhodium catalyst provides a straightforward means for the construction of various pyrrolidine rings from the corresponding primary amines. Preliminary mechanistic investigation suggests that the structure of the nitrene precursor plays a role in determining the nature of the resulting reactive intermediate.
Enantioselective synthesis of amines by combining photoredox and enzymatic catalysis in a cyclic reaction network
Guo, Xingwei,Okamoto, Yasunori,Schreier, Mirjam R.,Ward, Thomas R.,Wenger, Oliver S.
, p. 5052 - 5056 (2018/06/12)
Visible light-driven reduction of imines to enantioenriched amines in aqueous solution is demonstrated for the first time. Excitation of a new water-soluble variant of the widely used [Ir(ppy)3] (ppy = 2-phenylpyridine) photosensitizer in the p
