35973-27-4 Usage
General Description
AURORA 18051 is a chemical compound that is classified as a sesquiterpene lactone. It is a natural product derived from plants and is known for its anti-inflammatory and cytotoxic properties. It has been studied for its potential use in pharmaceuticals for treating various diseases, including cancer and inflammation-related disorders. AURORA 18051 has been shown to exhibit strong bioactivity against cancer cells and is being explored for its potential as a natural alternative for anti-cancer therapy. Additionally, its anti-inflammatory properties make it a promising candidate for the development of new treatments for conditions such as arthritis and inflammatory bowel disease. Overall, AURORA 18051 holds potential for a wide range of therapeutic applications due to its bioactive properties and natural origin.
Check Digit Verification of cas no
The CAS Registry Mumber 35973-27-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,9,7 and 3 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 35973-27:
(7*3)+(6*5)+(5*9)+(4*7)+(3*3)+(2*2)+(1*7)=144
144 % 10 = 4
So 35973-27-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H5Cl2NO3/c11-4-1-5-8(7(12)2-4)13-3-6(9(5)14)10(15)16/h1-3H,(H,13,14)(H,15,16)
35973-27-4Relevant articles and documents
Dichloro-4-quinolinol-3-carboxylic acid: Synthesis and antioxidant abilities to scavenge radicals and to protect methyl linoleate and DNA
Li, Guo-Xiang,Liu, Zai-Qun,Luo, Xu-Yang
experimental part, p. 1821 - 1827 (2010/06/21)
5,7-, 5,8-, 6,8-, 7,8-Dichloro-4-quinolinol-3-carboxylic acid (5,7-, 5,8-, 6,8-, 7,8-DCQA) together with 7-chloro-4-quinolinol-3-carboxylic acid (7-CQA) and 4-quinolinol-3-carboxylic acid (QA) were synthesized to investigate the antioxidant properties. 5,7-DCQA exhibited the highest ability to scavenge 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonate) cationic radical (ABTS+.), 2,2′-diphenyl-1-picrylhydrazyl (DPPH) and galvinoxyl radicals. 6,8-DCQA possessed the highest efficacy to protect methyl linoleate against 2,2′-azobis(2-amidinopropane)dihydrochloride (AAPH)-induced oxidation. 5,7-, 5,8-DCQA and QA were able to retard the β-carotene-bleaching in β-carotene-linoleic acid emulsion. In addition, 5,8- and 6,8-DCQA efficiently protected DNA against hydroxyl radical (.OH)-mediated oxidation, and 5,8-DCQA and 7-CQA were active to protect DNA against AAPH-induced oxidation. Furthermore, only 7-CQA can protect DNA against Cu2+/glutathione (GSH)-mediated oxidation. Dichloro-4-quinolinol-3-carboxylic acids were potent to be antiradical drugs, and were worthy to be researched pharmacologically.
