36027-16-4

Basic information

• Product Name: 5-ethyl-5-methyl-3-phenylhydantoin
• Synonyms: 5-ethyl-5-methyl-3-phenylhydantoin
• CAS NO: 36027-16-4
• Molecular Weight: 218.255
• Mol File: 36027-16-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-ethyl-5-methyl-3-phenylhydantoin(CAS DataBase Reference)
• NIST Chemistry Reference: 5-ethyl-5-methyl-3-phenylhydantoin(36027-16-4)
• EPA Substance Registry System: 5-ethyl-5-methyl-3-phenylhydantoin(36027-16-4)

Safety Data

• Hazardous Substances Data: 36027-16-4(Hazardous Substances Data)

Upstream product

• 591-50-4 iodobenzene 
• 5394-36-5 5-ethyl-5-methylimidazolidine-2,4-dione 

Relevant articles and documents

Copper-Mediated N-Arylations of Hydantoins

A set of two broadly applicable procedures for the N-arylation of hydantoins is reported. The first one relies on the use of stoichiometric copper(I) oxide under ligand- A nd base-free conditions and enables a clean regioselective arylation at the N3 nitrogen atom, while the second one is based on the use of catalytic copper(I) iodide and trans-N,N′-dimethylcyclohexane-1,2-diamine and promotes arylation at the N1 nitrogen atom. Importantly, the combination of these two procedures affords a straightforward entry to diarylated hydantoins.