36052-26-3Relevant articles and documents
POLY HETEROCYCLIC CONJUGATES AND THEIR PHARMACEUTICAL USES
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Paragraph 0039-0041, (2022/01/04)
Compounds of Formula (I) shown below and a pharmaceutical composition containing one of the compounds: Each of the variables is defined herein. Also disclosed is a method of treating a condition associated with uncontrolled cell growth with a compound of Formula (I).
Discovery of highly reactive peptide tag by ELISA-type screening for specific cysteine conjugation
Kurashige, Nobutaka,Fuchida, Hirokazu,Tabata, Shigekazu,Uchinomiya, Shohei,Ojida, Akio
supporting information, p. 3486 - 3489 (2017/07/07)
We report the discovery of a highly reactive peptide tag for the specific cysteine conjugation of proteins. Screening of cysteine-containing peptides using ELISA-type screening yielded a 19-amino acid tag (DCPPPDDAADDAADDAADD), named DCP3 tag, which enabl
Cation-halide transport through peptide pores containing aminopicolinic acid
Basak, Debajyoti,Sridhar, Sucheta,Bera, Amal K.,Madhavan, Nandita
supporting information, p. 4712 - 4717 (2016/06/09)
Synthetic pores that selectively transport ions of biological significance through membranes could be potentially used in medical diagnostics or therapeutics. Herein, we report cation-selective octapeptide pores derived from alanine and aminopicolinic acid. The ion transport mechanism through the pores has been established to be a cation-chloride symport. The cation-chloride co-transport is biologically essential for the efficient functioning of the central nervous system and has been implicated in diseases such as epilepsy. The pores formed in synthetic lipid bilayers do not exhibit any closing events. The ease of synthesis as well as infinite lifetimes of these pores provides scope for modifying their transport behaviour to develop sensors.