3612-18-8 Usage
Description
1-Ethyl-4-piperidone is an organic compound with the molecular formula C?H??NO. It is a heterocyclic compound featuring a piperidone ring, which is a six-membered ring containing both nitrogen and carbon atoms. 1-Ethyl-4-piperidone is known for its versatile chemical properties and potential applications in various industries.
Uses
Used in Pharmaceutical Industry:
1-Ethyl-4-piperidone is used as an intermediate in the synthesis of various pharmaceutical compounds. Its ability to form 3,5-bisarylmethylene-1-ethyl-4-piperidones makes it a valuable building block for creating complex molecules with potential therapeutic applications.
Used in Chemical Synthesis:
1-Ethyl-4-piperidone serves as a key component in the preparation of a range of chemical products. Its unique structure allows for further functionalization and modification, making it a useful starting material for the development of new compounds with specific properties and applications.
Synthesis Reference(s)
Journal of the American Chemical Society, 68, p. 1239, 1946 DOI: 10.1021/ja01211a028
Check Digit Verification of cas no
The CAS Registry Mumber 3612-18-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,1 and 2 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 3612-18:
(6*3)+(5*6)+(4*1)+(3*2)+(2*1)+(1*8)=68
68 % 10 = 8
So 3612-18-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H13NO/c1-2-8-5-3-7(9)4-6-8/h2-6H2,1H3/p+1
3612-18-8Relevant articles and documents
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Fuson et al.
, p. 1239 (1946)
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Discovery of tetrahydropyrido[4,3-d]pyrimidine derivatives for the treatment of neuropathic pain
Sharma, Monika,Deekshith, Vanamala,Semwal, Arvind,Sriram, Dharmarajan,Yogeeswari, Perumal
, p. 69 - 76 (2014/01/17)
A series of tetrahydropyridopyrimidine derivatives were synthesized and evaluated for neurotoxicity and peripheral analgesic activity followed by assessment of antiallodynic and antihyperalgesic potential in two peripheral neuropathic pain models, the chronic constriction injury (CCI) and partial sciatic nerve ligation (PSNL). Compounds (4b and 4d) exhibiting promising efficacies in four behavioral assays of allodynia and hyperalgesia (spontaneous pain, tactile allodynia, cold allodynia and mechanical hyperalgesia) were quantified for their ED50 values (15.12-65.10 mg/kg). Studies carried out to assess the underlying mechanism revealed that the compounds suppressed the inflammatory component of the neuropathic pain and prevented oxidative and nitrosative stress.
DIHYDROIMIDAZO [ 1, 5-F] PTERIDINES AS POLO-LIKE KINASE INHIBITORS
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Page/Page column 29, (2010/04/06)
The present invention provides PLK inhibitors of the formula (I) wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using the compounds.