361437-00-5

Basic information

• Product Name: 4-(4-Fluorophenoxy)phenylboronic acid
• Synonyms: 4-(4-Fluorophenoxy)phenylboronic acid;Boronic acid,B-[4-(4-fluorophenoxy)phenyl]-
• CAS NO: 361437-00-5
• Molecular Formula: C₁₂H₁₀BFO₃
• Molecular Weight: 232.0154032
• Mol File: 361437-00-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 374℃
• Flash Point: 180℃
• Appearance: /
• Density: 1.30
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-(4-Fluorophenoxy)phenylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Fluorophenoxy)phenylboronic acid(361437-00-5)
• EPA Substance Registry System: 4-(4-Fluorophenoxy)phenylboronic acid(361437-00-5)

Safety Data

• Hazardous Substances Data: 361437-00-5(Hazardous Substances Data)

Usage

General Description

4-(4-Fluorophenoxy)phenylboronic acid, also known as CAS No. 871477-41-7, is a type of boronic acid derivative with aromatic phenyl rings. Known for its chemical stability and reactivity, it comprises fluorine atom and boronic acid functionalities concurrently. It appears as a light yellow to white solid powder. This chemical is mainly involved in complex synthetic chemistry including Suzuki-Miyaura cross-coupling reactions, which are essential in producing various pharmaceuticals and biologically active compounds. Along with this, 4-(4-Fluorophenoxy)phenylboronic acid is also utilized in the manufacturing of organic light-emitting diodes (OLEDs). Handling and usage of this chemical should be done with protective gear as it might cause eye and skin irritation.

Upstream product

• 371-41-5 4-Fluorophenol 
• 589-87-7 1,4-bromoiodobenzene 
• 55102-99-3 1-bromo-4-(4-fluorophenoxy) benzene 
• 330-84-7 4-fluorophenoxybenzene 
• 73183-34-3 bis(pinacol)diborane 
• 5419-55-6 Triisopropyl borate 

Downstream Products

• 1027188-57-3 5-(tert-butyl-dimethyl-silanyloxymethyl)-3-[4-(4-fluoro-phenoxy)-phenyl]-2-oxo-2,5-dihydro-pyrrole-1-carboxylic acid tert-butyl ester 
• 1371596-31-4 C₂₀H₁₂ClFN₂O 
• 1371596-32-5 C₂₂H₁₅FN₂O 
• 1371595-84-4 (S)-2-{4-[4-(4-fluoro-phenoxy)-phenyl]-quinazolin-2-ylamino}-3-hydroxy-propionamide 
• 1578241-99-2 4-chloro-2-[4-(4-fluorophenoxy)phenyl]pyridine 
• 1578242-00-8 4-chloro-3-[4-(4-fluorophenoxy)phenyl]pyridine 
• 1127563-71-6 6-(4-(4-fluorophenoxy)phenyl)-4-chloropyridine-2-carbonitrile 
• 1354200-00-2 6-(4-(4-fluorophenoxy)phenyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one 

Relevant articles and documents

CYCLIC MOLECULES AS BRUTON'S TYROSINE KINASE INHIBITOR

The present invention relates to a novel molecule with protein tyrosine kinase inhibitory activity, and the synthesis and usage thereof. Specifically, the present invention relates to compound by formula A, pharmaceutically acceptable salts, hydrates or solvates thereof, and the synthesis and usage thereof.

Platinum(II) cyclometallates featuring broad emission bands and their applications in color-tunable OLEDs and high color-rendering WOLEDs

Two phosphorescent platinum(ii) cyclometallated complexes with phenoxy groups (1 and 2) have been developed. The modified organic ligands derived by combining the phenoxy moiety and 2-phenylpyridine conferred them with a more flexible structure, leading to superior intermolecular interaction properties of the resulting Pt(ii) metallophosphors. Because of the excimer formation induced by Pt(ii) complexes 1 and 2, the emission color can be tuned over a wide range from cyan to orange by simply increasing the concentration of the Pt(ii) metallophosphors. Inspired by their broad emission band, color tunability and outstanding electroluminescence (EL) performance, these two Pt(ii) phosphors complemented with blue fluorescent emitter 4,4′-bis(9-ethyl-3-carbazovinylene)-1,1′-biphenyl (BCzVBi) were employed in manufacturing high color-rendering white organic light-emitting devices (WOLEDs). In such simple two-emitter systems, 1-based WOLEDs exhibited reasonable EL performance with an external quantum efficiency (ηext) of 11.7%, luminance efficiency (ηL) of 29.1 cd A-1, power efficiency (ηp) of 16.9 lm W-1 and color rendering index (CRI) of 77, whereas 2-based WOLEDs demonstrated an ηext of 10%, ηL of 21.7 cd A-1, ηp of 10.7 lm W-1 and CRI of 88.