361460-41-5Relevant articles and documents
A convergent synthesis of the renin inhibitor SPP-100 using a nitrone intermediate
Dondoni, Alessandro,De Lathauwer, Geert,Perrone, Daniela
, p. 4819 - 4823 (2007/10/03)
The total synthesis of SPP-100 and its C-5 epimer involves the construction of the β-amino alcohol segment via addition of the Grignard reagent derived from 3-aryl-2-isopropyl-1-chloropropane to the nitrone functional group installed at C-4 of the pseudoe