3618-04-0 Usage
Description
4-HYDROXY-CYCLOHEXANECARBOXYLIC ACID ETHYL ESTER, also known as trans-Ethyl 4-hydroxycyclohexanecarboxylate, is an organic compound with the molecular formula C10H18O3. It is a colorless to pale yellow liquid with a fruity odor. This ester is characterized by its hydroxy and carboxyl groups, which allow it to participate in various chemical reactions and interactions with other molecules.
Uses
Used in Pharmaceutical Research:
4-HYDROXY-CYCLOHEXANECARBOXYLIC ACID ETHYL ESTER is used as a reagent for the discovery of Mer kinase inhibitors. These inhibitors are being investigated for their potential in treating pediatric acute lymphoblastic leukemia, a type of cancer that primarily affects children.
Used in Antiviral Research:
In the field of antiviral research, 4-HYDROXY-CYCLOHEXANECARBOXYLIC ACID ETHYL ESTER is utilized in the structural activity relationship study of piperidine-based derivatives. These derivatives are being explored as novel influenza virus inhibitors, with the aim of developing new treatments for influenza infections.
Used in Chemical Synthesis:
4-HYDROXY-CYCLOHEXANECARBOXYLIC ACID ETHYL ESTER can also be employed as an intermediate in the synthesis of various chemical compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure and reactivity make it a valuable building block in organic chemistry.
Used in Flavor and Fragrance Industry:
Due to its fruity odor, 4-HYDROXY-CYCLOHEXANECARBOXYLIC ACID ETHYL ESTER may find applications in the flavor and fragrance industry, where it can be used to create or enhance the scent of various products, such as perfumes, cosmetics, and food additives.
Check Digit Verification of cas no
The CAS Registry Mumber 3618-04-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,1 and 8 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 3618-04:
(6*3)+(5*6)+(4*1)+(3*8)+(2*0)+(1*4)=80
80 % 10 = 0
So 3618-04-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H16O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h7-8,10H,2-6H2,1H3/t7-,8-
3618-04-0Relevant articles and documents
HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS
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Page/Page column 106, (2019/01/17)
Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.
A biocatalytic/reductive etherification approach to substituted piperidinyl ethers
Kuethe, Jeffrey T.,Janey, Jacob M.,Truppo, Matthew,Arredondo, Juan,Li, Tao,Yong, Kelvin,He, Shuwen
, p. 4563 - 4570 (2014/06/10)
A synthetically useful protocol has been developed for the preparation of highly functionalized piperidinyl ethers. Biocatalytic reduction of cyclhexanones 7, 10, and 14 allows for the preparation of both cis- and trans diastereomers with an extremely high degree of stereochemical control. Reductive etherification of the corresponding trimethylsilylethers with 1-(benzyloxycarbonyl)-4-piperidinone 17 in the presence of triethylsilane and catalytic TMSO-Tf provides the desired piperidinyl ethers in good to excellent yields. Finally hygrogenolysis of the nitrogen protecting group leads to piperidinyl ethers in near quantitative yields. Application of the methodology to a range of piperidinyl ethers, including the core scaffolds of diphenylpyraline and ebastine, is also described.
IMIDAZOLE DERIVATIVES
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Page/Page column 60, (2013/02/27)
Described herein are compounds of formula (I), The compounds of formula I act as DGAT1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for hyperlipidemia, diabetes mellitus and obesity.
