36192-61-7

Basic information

• Product Name: (2-aminophenyl)(4'-methoxyphenyl)methanone
• Synonyms: (2-aminophenyl)(4'-methoxyphenyl)methanone;2-Amino-4'-methoxybenzophenone
• CAS NO: 36192-61-7
• Molecular Formula: C₁₄H₁₃NO₂
• Molecular Weight: 227.25852
• Mol File: 36192-61-7.mol
• Article Data: 34

Chemical Properties

• Melting Point: 77-77.5 °C
• Boiling Point: 428.3±30.0 °C(Predicted)
• Appearance: /
• Density: 1.172±0.06 g/cm3(Predicted)
• PKA: -0.25±0.10(Predicted)
• CAS DataBase Reference: (2-aminophenyl)(4'-methoxyphenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-aminophenyl)(4'-methoxyphenyl)methanone(36192-61-7)
• EPA Substance Registry System: (2-aminophenyl)(4'-methoxyphenyl)methanone(36192-61-7)

Safety Data

• Hazardous Substances Data: 36192-61-7(Hazardous Substances Data)

Usage

Description

(2-aminophenyl)(4'-methoxyphenyl)methanone is a chemical compound with the molecular formula C14H13NO2. It features a benzophenone structure with a 2-aminophenyl and a 4'-methoxyphenyl group attached, known for its diverse chemical reactivity and unique structural features.

Uses

Used in Pharmaceutical Research and Development:
(2-aminophenyl)(4'-methoxyphenyl)methanone is used as a catalyst and an intermediate in the synthesis of various pharmaceuticals and organic compounds. Its potential biological activities and medicinal properties make it a valuable compound in the field of pharmaceutical research and development.
Used in Catalyst Applications:
(2-aminophenyl)(4'-methoxyphenyl)methanone is utilized as a catalyst in chemical reactions, facilitating the process and improving the efficiency of synthesis, which is crucial for the production of various organic compounds and pharmaceuticals.

Upstream product

• 75127-50-3 N-[2-(4-methoxybenzoyl)phenyl]-4-(methyl)benzenesulfonamide 
• 100-66-3 methoxybenzene 
• 525-76-8 2-methyl-4-oxo-3,1-benzoxazine 
• 696-62-8 para-iodoanisole 
• 73376-03-1 (4-methoxyphenyl)(2-nitrophenyl)methanone 
• 42840-02-8 2-(Toluene-4-sulfonylamino)-benzoyl chloride 
• 6311-23-5 2-(toluene-4-sulfonylamino)-benzoic acid 
• 112219-63-3 (4-methoxyphenyl)magnesium iodide 
• 118-92-3 anthranilic acid 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 133776-41-7 anthranilic acid N-methoxy-N-methylamide 
• 552-16-9 ortho-nitrobenzoic acid 
• 610-14-0 2-nitrobenzyl chloride 
• 118-48-9 isatoic anhydride 

Downstream Products

• 408307-34-6 1-(2-amino-phenyl)-1-(4-methoxy-phenyl)-2-[2]pyridyl-ethanol 
• 91148-62-8 (2-Amino-phenyl)-bis-(4-methoxy-phenyl)-methanol 
• 34999-53-6 (2-aminophenyl)-(4-methoxyphenyl)methanol 
• 199168-43-9 4-(4-methoxy-phenyl)-3-methyl-cinnoline 
• 860563-29-7 2-amino-4'-hydroxy-benzophenone 
• 92247-84-2 2-amino-4'-methoxydiphenylmethane 
• 1071546-70-7 1-(2-amino-phenyl)-2-[2]quinolyl-1-(4-methoxy-phenyl)-ethanol 
• 113802-23-6 3-Aziridin-1-ylmethyl-4-(4-methoxy-phenyl)-quinolin-2-ylamine 
• 113802-28-1 4-(4-Methoxy-phenyl)-3-piperidin-1-ylmethyl-quinolin-2-ylamine 
• 37118-72-2 4-(p-methoxyphenyl)-2-(1H)-quinolinone 
• 103021-69-8 2-amino-4'-methoxytriphenylmethanol 
• 37892-45-8 2-azido-4'-methoxy-benzophenone 
• 93424-33-0 4-(4'-methoxyphenyl)-2-quinolone-3-acetic acid 
• 14427-38-4 6,12-bis-(4-methoxy-phenyl)-dibenzo[b,f][1,5]diazocine 

Relevant articles and documents

Dual Role of Anthranils as Amination and Transient Directing Group Sources: Synthesis of 2-Acyl Acridines

The transient directing group promoted C(sp2)-H functionalization of benzaldehydes with anthranils by a cationic rhodium(III) catalyst is described. Notably, anthranils have been used as both transient directing groups and amination sources to afford 2-acyl acridines through direct C-H amination followed by acid-mediated cyclization. A range of substrate scopes and functional group tolerance were observed.

Synthesis of 1-Amino-2,2,2-trifluoroalkylphosphonates from Alkene-Tethered Trifluoroacetimidoyl Chlorides

The reaction of alkene-tethered trifluoroacetimidoyl chlorides with trialkyl phosphites furnishes 1-amino-2,2,2-trifluoroalkylphosphonates. The products were generated in moderate to good yields, and the scalability of this process was showcased. Partial hydrolysis of the phosphonate moiety was achieved. The cyclization is proposed to occur via formation of an imidoyl phosphonate intermediate that becomes susceptible to nucleophilic attack at nitrogen through the strong electron-withdrawing groups at the imidoyl carbon.

Visible Light Induced Cyclization to Spirobi[indene] Skeletons from Functionalized Alkylidienecyclopropanes

In this paper, we revealed a metal-free and visible light photoinduced method for the rapid construction of spirobi[indene] skeletons, providing a simple and efficient way for easy access to spirobi[indene] scaffolds under mild conditions along with a broad substrate scope and good functional group tolerance.