36220-92-5Relevant articles and documents
Convenient synthesis of chlorohydrins from epoxides using zinc oxide: Application to 5,6-epoxysitosterol
Moghaddam, Firouz Matloubi,Saeidian, Hamdollah,Mirjafary, Zohreh,Javan, Marjan Jebeli,Farimani, Mehdi Moridi,Seirafi, Marjan
experimental part, p. 157 - 163 (2009/09/30)
Efficient synthesis of protected and unprotected chlorohydrins has been achieved by ring opening of epoxides with acetyl/benzoyl chloride and TMSCl using a catalytic amount of ZnO as a reusable catalyst. The applicability of ZnO is further extended by performing the cleavage of the natural product 5,6-epoxysitosterol with acetyl chloride.
Lanthanoid-catalyzed ring-opening reaction of epoxides with acyl halides
Taniguchi, Yuki,Tanaka, Shintaro,Kitamura, Tsugio,Fujiwara, Yuzo
, p. 4559 - 4560 (2007/10/03)
Eu(dpm)3 [dpm: dipivaloylmethanate] catalyzes the ring-opening reaction of epoxides with acyl halides affording the corresponding 2-haloalkyl esters. The stereochemical course was confirmed as trans-addition in the case of the reaction of cyclo
Reaction of Epoxides with Chlorocarbonylated Compounds Catalyzed by Hexaalkylguanidinium Chloride
Gros, P.,Perchec, P. Le,Senet, J. P.
, p. 4925 - 4930 (2007/10/02)
Silica-supported guanidinium chloride (PBGSiCl) exhibits efficient chemo- and regiospecific catalytic activity in the ring opening of epoxides with various electrophiles.This reaction allows the preparation of β-chloro esters and β-chloro chloroformates in high yield under neutral conditions which offer product stability and ease of product isolation.
