362596-61-0Relevant articles and documents
Substituted pyrimidine compound containing isothiourea group and preparation method and application thereof
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Paragraph 0213-0214; 0217-0218, (2019/10/15)
The invention relates to a substituted pyrimidine compound containing isothiourea perssad and being shown in the formula I and a preparation method and application thereof. The compound is simple in synthesis process, high in efficiency and low in cost. The in-vitro cell test indicates that the substituted pyrimidine compound containing isothiourea perssad has the good anti-tumor effect on HT29, HCT116, A549 and 1299 cells, and the substituted pyrimidine compound containing isothiourea perssad has good cell Golgi apparatus regioselectivity and imaging, can serve as anti-tumor medicine and cell Golgi apparatus fluorescent staining medicine, and has wide application prospects in biomedicine, wherein the formula I is shown in the specification.