36293-50-2Relevant articles and documents
Synthesis of α-difluoro and α-difluoro-β-trifluoroketo-derivatives as potential inhibitors for cholesterol ester hydrolase
David, Beatrice,Schuber, Francis
, p. 1673 - 1676 (2007/10/03)
Pancreatic Cholesterol Ester Hydrolase, a serine esterase, catalyzes the hydrolysis of cholesteryl esters in the gut. We report the convergent synthesis of α-difluoro-β-trifluoroketo-(5,10,15) and of α-difluoroketo-derivatives (22,23) as inhibitors of this enzyme that were designed to generate stable tetrahedral reaction intermediates.
Chiral Sulfoxides in Asymmetric Synthesis: A New Chiral Synthesis of Optically Active 4-Substituted Cyclohexylideneacetic Acid Esters
Solladie, Guy,Zimmermann, Richard,Bartsch, Richard,Walborsky, Harry M.
, p. 662 - 665 (2007/10/02)
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