36298-66-5

Basic information

• Product Name: 5(4H)-Isoxazolone, 4-(diphenylmethylene)-3-phenyl-
• CAS NO: 36298-66-5
• Molecular Formula: C22H15NO2
• Molecular Weight: 325.367
• Mol File: 36298-66-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5(4H)-Isoxazolone, 4-(diphenylmethylene)-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 5(4H)-Isoxazolone, 4-(diphenylmethylene)-3-phenyl-(36298-66-5)
• EPA Substance Registry System: 5(4H)-Isoxazolone, 4-(diphenylmethylene)-3-phenyl-(36298-66-5)

Safety Data

• Hazardous Substances Data: 36298-66-5(Hazardous Substances Data)

Upstream product

• 1227841-46-4 benzophenone O-3-propioloyl oxime 
• 41836-94-6 3-phenyl-4-benzoyl-isoxazol-5-one 

Downstream Products

• 188118-29-8 3,5-bis(4-methoxyphenyl)-1,2,4-oxadiazole 4-oxide 
• 20594-92-7 3,5-diphenyl-1,2,4-oxadiazole-4-oxide 
• 41837-02-9 3-phenyl-4-trityl-2H-isoxazol-5-one 
• 41837-03-0 4-(4-methoxy-trityl)-3-phenyl-2H-isoxazol-5-one 
• 41837-06-3 4-[diphenyl-(N'-phenyl-hydrazino)-methyl]-3-phenyl-2H-isoxazol-5-one 

Relevant articles and documents

Gold-catalyzed cyclization and subsequent arylidene group transfer of O-propioloyl oximes

Gold-catalyzed cyclizations of O-propioloyl oximes via C-N bond formation followed by arylidene group transfer were successfully carried out to afford the corresponding 4-arylideneisoxazol-5(4H)-ones in good to excellent yields. As an example, (E)-benzaldehyde O-3-phenylpropioloyl oxime (1a) was reacted in acetonitrile at 25 °C in the presence of Au(PPh3)NTf2 (5 mol %) to give 4-benzylidene-3-phenylisoxazol-5(4H)-one (2a) in 90% yield. On the basis of crossover experiments, the arylidene "migration" was shown to proceed in an intermolecular manner.