363191-25-7 Usage
General Description
3-[[(1,1-Dimethylethoxy)carbonyl]amino]-D-alanine methyl ester is a complex chemical compound. Its molecular structure consists of a D-alanine backbone — an important component related to proteins in our body — with a dimethylethoxy carbonyl group and a methyl ester attached to its structure. These additional groups make this compound different from the natural D-alanine. The presence of the carbonyl group can add to the reactivity of this compound, potentially forming different derivatives when interacting with other chemical substances. Given its specific structure, the compound may boast extensive use in scientific research, particularly in protein and biochemistry studies. There is little information available on its safety, physico-chemical properties, or environmental impact.
Check Digit Verification of cas no
The CAS Registry Mumber 363191-25-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,3,1,9 and 1 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 363191-25:
(8*3)+(7*6)+(6*3)+(5*1)+(4*9)+(3*1)+(2*2)+(1*5)=137
137 % 10 = 7
So 363191-25-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H18N2O4/c1-9(2,3)15-8(13)11-5-6(10)7(12)14-4/h6H,5,10H2,1-4H3,(H,11,13)/t6-/m1/s1
363191-25-7Relevant articles and documents
Capped diaminopropionamide-glycine dipeptides are inhibitors of CC chemokine receptor 2 (CCR2)
Carter, Percy H.,Brown, Gregory D.,Friedrich, Sarah R.,Cherney, Robert J.,Tebben, Andrew J.,Lo, Yvonne C.,Yang, Gengjie,Jezak, Heather,Solomon, Kimberly A.,Scherle, Peggy A.,Decicco, Carl P.
, p. 5455 - 5461 (2008/12/23)
A new series of CCR2 antagonists has been discovered that incorporates intramolecular hydrogen bonding as a strategy for rigidifying the scaffold. The structure-activity relationship was established through initial systematic modification of substitution pattern and chain length, followed by independent optimization of three different substituents (benzylamine, carboxamide, and benzamide). Several of the acyclic compounds display 10-30 nM binding affinity for CCR2. Moreover, these antagonists are able to block both MCP-1-induced Ca2+ flux and monocyte chemotaxis, and are selective for binding to CCR2 over CCR1 and CCR3.
