36342-07-1

Basic information

• Product Name: N-N-PROPYLMALEAMIC ACID, 98
• Synonyms: N-N-PROPYLMALEAMIC ACID, 98;4-oxo-4-(propylamino)isocrotonic acid;(Z)-4-Oxo-4-(propylamino)-2-butenoic acid;N-n-Propylmaleamidic acid
• CAS NO: 36342-07-1
• Molecular Formula: C₇H₁₁NO₃
• Molecular Weight: 157.16714
• EINECS: 252-986-9
• Mol File: 36342-07-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 376.4 °C at 760 mmHg
• Flash Point: 181.5 °C
• Appearance: /
• Density: 1.136 g/cm³
• Vapor Pressure: 1.05E-06mmHg at 25°C
• Refractive Index: 1.486
• CAS DataBase Reference: N-N-PROPYLMALEAMIC ACID, 98(CAS DataBase Reference)
• NIST Chemistry Reference: N-N-PROPYLMALEAMIC ACID, 98(36342-07-1)
• EPA Substance Registry System: N-N-PROPYLMALEAMIC ACID, 98(36342-07-1)

Safety Data

• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36:Wear suitable prot
• Hazardous Substances Data: 36342-07-1(Hazardous Substances Data)

Usage

Description

N-N-PROPYLMALEAMIC ACID, 98 is an organic compound that serves as a valuable research reagent in the field of organic synthesis and various chemical processes. It is known for its unique chemical properties that make it suitable for a wide range of applications.

Uses

Used in Research and Development:
N-N-PROPYLMALEAMIC ACID, 98 is used as a research reagent for organic synthesis and other chemical processes. Its unique chemical properties make it a valuable tool for scientists and researchers in the development of new compounds and materials.
Used in Pharmaceutical Industry:
N-N-PROPYLMALEAMIC ACID, 98 is used as an intermediate in the synthesis of various pharmaceutical compounds. Its versatility in chemical reactions allows for the creation of a wide range of drug candidates with potential therapeutic applications.
Used in Chemical Synthesis:
N-N-PROPYLMALEAMIC ACID, 98 is used as a building block in the synthesis of various organic compounds. Its reactivity and functional groups make it a useful component in the development of new molecules with specific properties and applications.
Used in Material Science:
N-N-PROPYLMALEAMIC ACID, 98 can be used as a component in the development of new materials with unique properties. Its chemical structure allows for the creation of materials with specific characteristics, such as improved strength, flexibility, or chemical resistance.

InChI:InChI=1/C7H11NO3/c1-2-5-8-6(9)3-4-7(10)11/h3-4H,2,5H2,1H3,(H,8,9)(H,10,11)/b4-3+

Upstream product

• 108-31-6 maleic anhydride 
• 107-10-8 propylamine 

Downstream Products

• 21746-40-7 propylmaleimide 
• 675876-25-2 but-2-enedioic acid benzyl-{benzylcarbamoyl-[1-(2-nitro-benzenesulfonyl)-1H-pyrrol-2-yl]-methyl}-amide propylamide 

Relevant articles and documents

Synthesis and antimicrobial activities of N-substituted imides

In the field of our research programs concerning novel antimicrobial agents, a series of N-substituted imides was synthesized. These compounds were obtained by cyclization of amido-acids in acetic anhydride/sodium acetate or hexamethyldisilazane/zinc bromide for the hydroxy-aromatic derivatives. The hydroxy-alkyl maleimides were directly prepared by condensation of the corresponding amino-alcohol with maleic anhydride in boiling toluene. Most of N-substituted maleimides showed an interesting antimicrobial activity towards bacteria from the ATCC collection (Staphylococcus aureus ATCC 25923, Enterococcus faecalis ATCC 29212, Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 27853) but the MIC values for P. aeruginosa were always high (128 μg/ml). The imides with alkyl substituents showed higher activities than aromatic analogues with MIC values in the range of 8-32 μg/ml. Comparatively, succinimides were practically inactive.