36364-49-5 Usage
Description
Imidazole is a five-membered heterocyclic compound with the molecular formula C3H4N2, characterized by its versatile chemical properties and wide-ranging applications across various industries.
Used in Pharmaceutical Industry:
Imidazole is used as a building block for the synthesis of pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
Imidazole serves as a key component in the synthesis of agrochemicals, aiding in the creation of effective products for agricultural applications.
Used in Organic Synthesis:
Imidazole is utilized as a versatile building block for the synthesis of various organic compounds, enhancing the scope of chemical reactions and product development.
Used in Metal Complex Chemistry:
Imidazole acts as a coordination ligand in metal complex chemistry, playing a crucial role in the formation and stabilization of metal complexes.
Used in Biochemical and Molecular Biology Research:
Imidazole is employed as a buffer, maintaining stable pH conditions in biochemical and molecular biology experiments, thus facilitating accurate research outcomes.
Used in Antimicrobial Applications:
Imidazole derivatives have been studied for their antimicrobial properties, offering potential as agents against various types of infections.
Used in Antifungal Applications:
Imidazole derivatives exhibit antifungal properties, making them valuable in the development of treatments for fungal infections.
Used in Antioxidant Applications:
Imidazole derivatives have been investigated for their antioxidant capabilities, suggesting their potential use in preventing oxidative damage in biological systems.
Used in Anti-inflammatory Applications:
Imidazole derivatives have shown anti-inflammatory properties, indicating their possible use in the development of treatments for inflammatory conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 36364-49-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,3,6 and 4 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 36364-49:
(7*3)+(6*6)+(5*3)+(4*6)+(3*4)+(2*4)+(1*9)=125
125 % 10 = 5
So 36364-49-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H6O3.C3H4N2/c8-6-4-2-1-3-5(6)7(9)10;1-2-5-3-4-1/h1-4,8H,(H,9,10);1-3H,(H,4,5)
36364-49-5Relevant articles and documents
Toxicity reduction of imidazolium-based ionic liquids by the oxygenation of the alkyl substituent
Vrane?,Tot,Jovanovi?-?anta,Karaman,Do?i?,Te?anovi?,Koji?,Gad?uri?
, p. 96289 - 96295 (2016)
In this work, five different salicylate based ionic liquids were prepared in order to study their toxicity: 1-butyl-3-methylimidazolium salicylate, [bmim][Sal], 1-(4-hydroxy-2-oxybutyl)-3-methylimidazolium salicylate, [OHC2OC2mim][Sal], 1-(3-hydroxypropyl)-3-methylimidazolium salicylate, [OHC3mim][Sal], 1-ethoxyethyl-3-methylimidazolium salicylate, [C2OC2mim][Sal] and imidazolium salicylate [Im][Sal]; aquatic organisms (Artemia salina) and a human non-tumor cell line (normal fetal lung fibroblasts, MRC-5) were also used in the investigation. The introduction of polar groups (in the form of hydroxide and/or ether group) into the alkyl side chain of the imidazolium cation, and their influence on the reduction of the ionic liquid's toxicity, were also demonstrated. The results indicate that the toxicity against A. salina and cytotoxicity against the healthy cell line of lipophobic ionic liquids were significantly lower than for the non-functionalized analogues, and are the same order of magnitude as the reference standard sodium salicylate. These facts open up the possibility of designing new non-toxic ionic liquids that can be used as active pharmaceutical ingredients in liquid form, adjusting only the lipophilicity of the cations by introducing polar oxygen groups into the side alkyl chain of the cation.
