365253-37-8 Usage
General Description
3-(1-Methyl-1H-indol-3-yl)-4-[1-[1-(2-pyridinylmethyl)-4-piperidinyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione hydrochloride is a chemical compound that is used in scientific research. It is a hydrochloride salt form of a pyrrolopyrrole compound, which is a potent and selective inhibitor of the protein kinase called cyclin-dependent kinase 7 (CDK7). CDK7 is an important enzyme involved in the regulation of cell cycle progression and transcription. 3-(1-Methyl-1H-indol-3-yl)-4-[1-[1-(2-pyridinylmethyl)-4-piperidinyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione hydrochloride has shown potential as a therapeutic agent for the treatment of various diseases, including cancer, by targeting the dysregulation of cell cycle and gene expression. Further research is ongoing to explore its potential applications in medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 365253-37-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,5,2,5 and 3 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 365253-37:
(8*3)+(7*6)+(6*5)+(5*2)+(4*5)+(3*3)+(2*3)+(1*7)=148
148 % 10 = 8
So 365253-37-8 is a valid CAS Registry Number.
365253-37-8Relevant articles and documents
CRYSTALLINE 2,5-DIONE-3-(1-METHYL-1H-INDOL-3-YL)-4-[1-(PYRIDIN-2-YLMETHYL)PIPERIDIN-4-YL]-1H-INDOL-3-YL]-1H-PYRROLE MONO-HYDROCHLORIDE
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Page/Page column 14, (2010/11/30)
The present invention relates to crystalline 2,5-dione-3-(1-methyl-1H-indol-3-yl)-4-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1H-indol-3-yl]-1H-pyrrole mono-hydrochloride salt, a pharmaceutical formulation containing said salt and to methods for treating can
