367506-67-0Relevant articles and documents
Identification of novel microsomal prostaglandin E2synthase-1 (mPGES-1) lead inhibitors from Fragment Virtual Screening
Lauro, Gianluigi,Manfra, Michele,Pedatella, Silvana,Fischer, Katrin,Cantone, Vincenza,Terracciano, Stefania,Bertamino, Alessia,Ostacolo, Carmine,Gomez-Monterrey, Isabel,De Nisco, Mauro,Riccio, Raffaele,Novellino, Ettore,Werz, Oliver,Campiglia, Pietro,Bifulco, Giuseppe
, p. 278 - 287 (2017)
Identification of new microsomal prostaglandin E2synthase-1 (mPGES-1) inhibitors is currently sought for the treatment of cancer and inflammation. Here we show the results of a Fragment Virtual Screening campaign using the X-ray crystal structu