369-53-9Relevant articles and documents
Cobalt-based nanoparticles prepared from MOF-carbon templates as efficient hydrogenation catalysts
Murugesan, Kathiravan,Senthamarai, Thirusangumurugan,Sohail, Manzar,Alshammari, Ahmad S.,Pohl, Marga-Martina,Beller, Matthias,Jagadeesh, Rajenahally V.
, p. 8553 - 8560 (2018/11/30)
The development of efficient and selective nanostructured catalysts for industrially relevant hydrogenation reactions continues to be an actual goal of chemical research. In particular, the hydrogenation of nitriles and nitroarenes is of importance for the production of primary amines, which constitute essential feedstocks and key intermediates for advanced chemicals, life science molecules and materials. Herein, we report the preparation of graphene shell encapsulated Co3O4- and Co-nanoparticles supported on carbon by the template synthesis of cobalt-terephthalic acid MOF on carbon and subsequent pyrolysis. The resulting nanoparticles create stable and reusable catalysts for selective hydrogenation of functionalized and structurally diverse aromatic, heterocyclic and aliphatic nitriles, and as well as nitro compounds to primary amines (>65 examples). The synthetic and practical utility of this novel non-noble metal-based hydrogenation protocol is demonstrated by upscaling several reactions to multigram-scale and recycling of the catalyst.
PRODUCTION PROCESS OF AMINOMETHYL GROUP-CONTAINING BENZAMIDE COMPOUND
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Page/Page column 12, (2008/06/13)
ABSTRACT There is provided a process for producing an aminomethyl group-containing benzamide compound represented by the general formula (II):wherein -CONH2 and -X represent a substituent on the benzene ring and -CONH2 exists at the meta- or para-position
5-Substituted-3-aminoalkyl indole derivatives
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, (2008/06/13)
Compounds are disclosed of the general formula (I) STR1 wherein R1 represents halogen, alkyl, alkoxy or hydroxyl, or a group NRa Rb or CONa Rb, where Ra and Rb are hydrogen, alkyl or alkenyl or with the nitrogen atom form a saturated monocyclic 5 to 7-membered ring; R2 represents hydrogen or alkyl; R3 and R4 represent hydrogen, C1-3 alkyl or propenyl or R3 and R4 together form an aralkylidene group; Alk represents a C2-3 alkylene chain; n and m, are integers of 1 to 4 or n is zero, and their physiologically acceptable salts and solvates. The compounds are described as useful in treating pain originating from dilatation of the cranial vasculature in particular migraine and cluster headache and can be formulated in conventional manner as pharmaceutical compositions with carriers or excipients for administration by any convenient route.