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37115-45-0

37115-45-0

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37115-45-0 Usage

Chemical Properties

Light Green Solid

Uses

A metabolite of Triazolam (T767380).

Biochem/physiol Actions

Triazolam metabolite

Check Digit Verification of cas no

The CAS Registry Mumber 37115-45-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,7,1,1 and 5 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 37115-45:
(7*3)+(6*7)+(5*1)+(4*1)+(3*5)+(2*4)+(1*5)=100
100 % 10 = 0
So 37115-45-0 is a valid CAS Registry Number.
InChI:InChI=1/C17H12Cl2N4O/c18-10-5-6-14-12(7-10)17(11-3-1-2-4-13(11)19)20-8-15-21-22-16(9-24)23(14)15/h1-7,24H,8-9H2

37115-45-0 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail

  • Sigma

  • (H2529)  α-Hydroxytriazolam  

  • 37115-45-0

  • H2529-5MG

  • 2,669.94CNY

  • Detail

  • Cerilliant

  • (T-911)  α-Hydroxytriazolam solution  1.0 mg/mL in methanol, ampule of 1 mL, certified reference material

  • 37115-45-0

  • T-911-1ML

  • 1,053.00CNY

  • Detail

  • Cerilliant

  • (T-915)  α-Hydroxytriazolam solution  100 μg/mL in methanol, ampule of 1 mL, certified reference material

  • 37115-45-0

  • T-915-1ML

  • 263.25CNY

  • Detail

37115-45-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name α-Hydroxytriazolam

1.2 Other means of identification

Product number -
Other names [8-chloro-6-(2-chlorophenyl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-1-yl]methanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:37115-45-0 SDS

37115-45-0Downstream Products

37115-45-0Relevant articles and documents

Expression and characterization of cynomolgus monkey cytochrome cyp3a4 in a novel human embryonic kidney cell-based mammalian systems

Selvakumar, Sindhuja,Bhutani, Priyadeep,Ghosh, Kaushik,Krishnamurthy, Prasad,Kallipatti, Sanjith,Selvam, Sabariya,Ramarao, Manjunath,Mandlekar, Sandhya,Sinz, Michael W.,Rodrigues, A. David,Subramanian, Murali

, p. 369 - 376 (2014)

Cynomolgus monkeys are a commonly used species in preclinical drug discovery, and have high genetic similarity to humans, especially for the drug-metabolizing cytochrome P450s. However, species differences are frequently observed in the metabolism of drug

Triazolobenzodiazepine derivatives

-

, (2008/06/13)

Compounds of the class of 6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine-1-lower alkanols, and their ethers and esters, 1-(fluoro-lower alkyl)-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines and the 5-oxides and pharmaceutically acceptable acid addition salts thereof have central depressant properties, in particular antiaggressive and anticonvulsant actions, and are active ingredients for pharmaceutical compositions. Specific embodients are 6-phenyl-8-chloro-4H-s-triazolo[4,3-a][1,4]benzodiazepine-1-methanol and 1-(fluoromethyl)6-phenyl-8-chloro-4H-s-triazolo[4,3-a][1,4]benzodiazepine.

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