37289-15-9

Basic information

• Product Name: CREATININE DEIMINASE
• Synonyms: CREATININE IMINOHYDROLASE, CORYNEBACTERIUM;creatinine deaminase;creatinine deiminase microbial;CREATININE DEIMINASE extrapure;EC 3.5.4.21;CREATININE DEIMINASE;CREATININE DEMINASE;CREATININE IMINOHYDROLASE
• CAS NO: 37289-15-9
• Molecular Weight: 0
• EINECS: 253-449-1
• Mol File: 37289-15-9.mol
• Article Data: 0

Chemical Properties

• Appearance: /lyophilized powder
• Storage Temp.: −20°C
• CAS DataBase Reference: CREATININE DEIMINASE(CAS DataBase Reference)
• NIST Chemistry Reference: CREATININE DEIMINASE(37289-15-9)
• EPA Substance Registry System: CREATININE DEIMINASE(37289-15-9)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 37289-15-9(Hazardous Substances Data)

Usage

Description

Creatinine deiminase, an enzyme with significant biotechnological relevance, catalyzes the conversion of creatinine to creatine. This enzyme is produced by specific bacteria and plays a crucial role in the management of creatinine levels, a waste product of muscle metabolism that is typically excreted by the kidneys. Elevated blood levels of creatinine are indicative of kidney dysfunction, making creatinine deiminase a valuable tool in both therapeutic and diagnostic contexts.

Uses

Used in Biotechnology:
Creatinine deiminase is used as an enzymatic agent for the removal of creatinine from blood and urine samples. This application is vital for accurate assessment and monitoring of kidney function, as well as for the development of novel diagnostic tests that can detect and measure kidney impairment.
Used in Therapeutic Applications for Kidney Disease:
In the medical field, creatinine deiminase is utilized as a potential therapeutic agent to lower creatinine levels in patients suffering from kidney disease. By converting creatinine to creatine, the enzyme may help alleviate the burden on the kidneys and improve overall kidney function, offering a promising avenue for the treatment of renal disorders.
Used in Diagnostic Development:
Creatinine deiminase also serves as a key component in the creation of innovative diagnostic tests designed to assess kidney function. Its ability to convert creatinine provides a measurable outcome that can be used to evaluate the effectiveness of treatments and monitor the progression of kidney-related diseases.