373604-28-5 Usage
Description
1-PIPERIDINECARBOXYLIC ACID, 3-FLUORO-4-HYDROXY-, 1,1-DIMETHYLETHYL ESTER, also known as 3-Fluoro-4-hydroxy-1-piperidinecarboxylic Acid tert-Butyl Ester, is a chemical compound with a complex structure that features a piperidine ring, a fluorine atom, a hydroxyl group, and a 1,1-dimethylethyl ester group. 1-PIPERIDINECARBOXYLIC ACID, 3-FLUORO-4-HYDROXY-, 1,1-DIMETHYLETHYL ESTER is characterized by its potential applications in the pharmaceutical industry, particularly in the development of therapeutic agents.
Uses
Used in Pharmaceutical Industry:
1-PIPERIDINECARBOXYLIC ACID, 3-FLUORO-4-HYDROXY-, 1,1-DIMETHYLETHYL ESTER is used as a key intermediate compound for the preparation of therapeutic GPR 119 modulators. GPR 119 is a G protein-coupled receptor that plays a role in glucose homeostasis and has been identified as a potential target for the treatment of type 2 diabetes and obesity. 1-PIPERIDINECARBOXYLIC ACID, 3-FLUORO-4-HYDROXY-, 1,1-DIMETHYLETHYL ESTER's unique structure allows it to interact with GPR 119, modulating its activity and potentially leading to improved glucose control and weight management in patients.
Check Digit Verification of cas no
The CAS Registry Mumber 373604-28-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,3,6,0 and 4 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 373604-28:
(8*3)+(7*7)+(6*3)+(5*6)+(4*0)+(3*4)+(2*2)+(1*8)=145
145 % 10 = 5
So 373604-28-5 is a valid CAS Registry Number.
373604-28-5Relevant articles and documents
SPIRO[CYCLOBUTANE-1,3'-INDOLIN]-2'-ONE DERIVATIVES AS BROMODOMAIN INHIBITORS
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, (2017/01/02)
The present invention provides novel spiro[cyclobutane-1,3'-indolin]-2'- derivatives of formula (I) in which Cy R1, R2, R4, L and 'm' are have the meaning given in the specification, and pharmaceutically acceptable salts thereof. The compounds of formula (I) are useful as bromodomain inhibitors in the treatment or prevention of diseases or disorders where bromodomain inhibition is desired.
COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF MEK
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, (2015/02/25)
The present invention relates to compounds of formula I: in which n, R1, R2, R3a, R4 and R5 are defined in the Summary of the Invention; capable of inhibiting the activity of MEK. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of hyperproliferative diseases like cancer.
BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY
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Paragraph 0600, (2015/06/25)
The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.