37458-38-1

Basic information

• Product Name: 5H-Pyrrolo[3,4-b]pyridine-5,7(6H)-dione, 6-(4-chlorophenyl)-
• CAS NO: 37458-38-1
• Molecular Formula: C13H7ClN2O2
• Molecular Weight: 258.664
• Mol File: 37458-38-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5H-Pyrrolo[3,4-b]pyridine-5,7(6H)-dione, 6-(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5H-Pyrrolo[3,4-b]pyridine-5,7(6H)-dione, 6-(4-chlorophenyl)-(37458-38-1)
• EPA Substance Registry System: 5H-Pyrrolo[3,4-b]pyridine-5,7(6H)-dione, 6-(4-chlorophenyl)-(37458-38-1)

Safety Data

• Hazardous Substances Data: 37458-38-1(Hazardous Substances Data)

Upstream product

• 4664-00-0 2,3-pyridinedicarboximide 
• 106-47-8 4-chloro-aniline 
• 699-98-9 Pyridine-2,3-dicarboxylic anhydride 
• 23439-87-4 6-hydroxy-5H-pyrrolo[3,4-b]pyridine-5,7-(6H)-dione 

Relevant articles and documents

Novel and versatile methodology for synthesis of cyclic imides and evaluation of their cytotoxic, DNA binding, apoptotic inducing activities and molecular modeling study

Versatile method has been developed for synthesis of N-substituted imides. Thus, acid anhydrides, imides and dicarboxylic acids were successfully subjected to dehydrative cyclization with substituted amines using DPPOx and Et3N to afford N-substituted imides under mild conditions. The DNA binding and apoptosis induction were investigated with regard to their potential utility as cytotoxic agents. Molecular modeling methods are used to study the cytotoxic activity of the active compounds by means of molecular and quantum mechanics.

New synthesis of pyrido[2,3-d] and [3,2-d]oxazines

N-Hydroxyquinolinimide 1 reacts with each of aromatic arnines, hydrazine hydrate and aromatic hydrocarbons to give arylcarbamoyl pyridines 2, pyrrolopyridines 3, pyridopyridazines 4 and pyridooxazinones 5 and 6. The heterocycles 5 and 6 can be transformed