37464-90-7Relevant articles and documents
-
Lewis et al.
, p. 5321,5322 (1952)
-
A SIMPLE SYNTHESIS OF (+/-) 4-DEMETHOXYDAUNOMYCINONE
Rao, Rama A. V.,Deshpande, V. H.,Reddy, Laxma N.
, p. 2661 - 2664 (1980)
A new and simple synthesis of 4-demethoxy-7-deoxydaunomycinone has been carried out essentially in three steps starting from 1,4-dimethoxy-6-tetralone.
Synthesis of anthracyclinone precursor: 5,12-dihydroxy-1,3,4- trihydronaphthacene-2,6,11-quinone
Tririya, Gasirat,Zanger, Murray
, p. 3047 - 3059 (2007/10/03)
Two practical and efficient approaches for preparing large quantities of 5,12-dihydroxy-1,3,4-trihydronaphthacene-2,6,11-quinone 9 are described. Both synthetic approaches involve a simple route with a fewer number of steps and utilize readily available and inexpensive starting materials. Large-scale production of this precursor may prove to be useful for further research involving the synthesis of antineoplastic anthracyclines and development of their analogs with increased activity and decreased toxicity.
RING-SUBSTITUTED 2-AMINO-1,2,3,4-TETRAHYDRONAPTHALENES
-
, (2008/06/13)
-