375854-57-2Relevant articles and documents
Visible light catalyzed synthesis of quinolines from (aza)-Morita-Baylis-Hillman adducts
Chaturvedi, Atul Kumar,Rastogi, Namrata
, p. 8155 - 8159 (2018/11/23)
A mild and efficient protocol for the synthesis of quinoline scaffolds from (aza)-MBH adducts under visible light catalysis has been established. The reaction involves visible light catalyzed generation of amidyl radicals from (aza)-MBH adducts followed by intramolecular radical cyclization. The reaction exhibits a wide substrate scope, good functional group tolerance and high regioselectivity. This is the first example of utilizing (aza)-MBH adducts for the generation of amidyl radicals and synthesizing aza-heterocycles under visible light photoredox catalyzed reaction conditions.
A one-step synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid esters from o -nitrobenzaldehydes
Venkatesan, Hariharan,Hocutt, Frances M.,Jones, Todd K.,Rabinowitz, Michael H.
supporting information; experimental part, p. 3488 - 3491 (2010/08/03)
A straightforward and efficient one-step procedure for the synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid ethyl esters is described. The simple reductive cyclization is carried out by treating various substituted o-nitrobenzaldehydes with inex