37663-44-8

Basic information

• Product Name: 4-SPIRO-[1-PHTHALAN]PIPERIDINE HYDROCHLORIDE
• Synonyms: 4-SPIRO-[1-PHTHALAN]PIPERIDINE HYDROCHLORIDE;3H-Spiro[Isobenzofuran-1,4''-Piperidine] Hcl;1,3-Dihydrospiro[isobenzofuran-1,4'-piperidine] hydrochloride;3H-Spiro[isobenzofuran-1,4'-piperidine] hydrochloride;Spiro[phthalan-1,4'-piperidine] hydrochloride;spiro[isobenzofuran-1(3H)-4'-piperidine] Monohydrochloride;Spiro[isobenzofuran-1(3H),4'-piperidine] Hydrochloride;3H-Spiro[2-benzofuran-1,4'-piperidine] hydrochloride
• CAS NO: 37663-44-8
• Molecular Formula: C₁₂H₁₅NO*ClH
• Molecular Weight: 225.71
• Product Categories: Pyridines
• Mol File: 37663-44-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 4-SPIRO-[1-PHTHALAN]PIPERIDINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-SPIRO-[1-PHTHALAN]PIPERIDINE HYDROCHLORIDE(37663-44-8)
• EPA Substance Registry System: 4-SPIRO-[1-PHTHALAN]PIPERIDINE HYDROCHLORIDE(37663-44-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 37663-44-8(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 37663-44-8 differently. You can refer to the following data:
1. Spiro[isobenzofuran-1(3H),4'-piperidine] is a (spiro)(hetero)cyclic amides as modulator of 11-β hydroxysteroid dehydrogenase type 1.
2. Spiro[isobenzofuran-1(3H),4''-piperidine] is a (spiro)(hetero)cyclic amides as modulator of 11-β hydroxysteroid dehydrogenase type 1.

Upstream product

• 54596-09-7 1'-benzyl-3H-spiro[isobenzofuran-1,4'-piperidine]; hydrochloride 

Downstream Products

• 56657-97-7 1-(4-fluoro-phenyl)-4-(3H-spiro[isobenzofuran-1,4'-piperidin]-1'-yl)-butan-1-one 
• 1152617-83-8 2,3-dichloro-4-(3H-spiro[2-benzofuran-1,4'-piperidine]-1'-yl)methylpyridine 

Relevant articles and documents

CYCLOALKANOPYRIDINE DERIVATIVE

Provided are cycloalkanopyridine derivatives of formula [I]: [wherein the symbols are the same as those stated in the description]. The compounds act as a nociceptin receptor antagonist, and are useful as medicines for diseases associated with a nociceptin receptor, for example, as a reliever against tolerance to a narcotic analgesic; a reliever against dependence on or addiction to a narcotic analgesic; an analgesic enhancer; an antiobesitic or appetite suppressor; a treating or prophylactic agent for cognitive impairment and dementia/amnesia; an agent for treating developmental cognitive abnormality; a remedy for schizophrenia; an agent for treating neurodegenerative diseases; an anti-depressant or treating agent for affective disorder; a treating or prophylactic agent for diabetes insipidus; a treating or prophylactic agent for polyuria; or a remedy for hypotension.