377047-49-9

Basic information

• Product Name: Pyridazine, 3-[1,1'-biphenyl]-4-yl-6-chloro-
• CAS NO: 377047-49-9
• Molecular Formula: C16H11ClN2
• Molecular Weight: 266.73
• Mol File: 377047-49-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Pyridazine, 3-[1,1'-biphenyl]-4-yl-6-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridazine, 3-[1,1'-biphenyl]-4-yl-6-chloro-(377047-49-9)
• EPA Substance Registry System: Pyridazine, 3-[1,1'-biphenyl]-4-yl-6-chloro-(377047-49-9)

Safety Data

• Hazardous Substances Data: 377047-49-9(Hazardous Substances Data)

Upstream product

• 260353-13-7 6-biphenyl-3-(2H)-pyridazinone 
• 260353-11-5 6-biphenyl-4-yl-4-(5-oxo-1,3-diphenyl-4,5-dihydro-1H-pyrazol-4-yl)-4,5-dihydro-2H-pyridazin-3-one 
• 71149-96-7 β-(4-phenylbenzoyl)acrylic acid 
• 92-66-0 4-bromo-1,1'-biphenyl 
• 144432-80-4 2-(biphenyl-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 89089-18-9 3-bromo-6-chloropyridazine 
• 36330-85-5 3-(p-phenyl)benzoylpropionic acid 
• 92-52-4 biphenyl 
• 52239-89-1 6-biphenyl-4-yl-4,5-dihydro-2H-pyridazin-3-one 
• 4845-49-2 1,3-diphenyl-5-oxo-4,5-dihydro-1H-pyrazole 

Downstream Products

• 88490-32-8 (6-biphenyl-4-yl-pyridazin-3-yl)-hydrazine 
• 1268133-98-7 3-phenyl-6-(4'-biphenyl)-1,2,4-triazolo[4,3-b]pyridazine 
• 260353-13-7 6-biphenyl-3-(2H)-pyridazinone 

Relevant articles and documents

Construction of Vesicles, Micro/Nanorods and Ultralong Nanotubes through the Self-Assembly of Non-Classical Amphiphiles with Rigid Conformation

Amphiphilic molecules have long been regarded as an important class of supramolecular building blocks for the fabrication of nanomaterials. While most previous researches have mainly focused on amphiphlies with flexible structures, in this work, four novel amphiphiles possessing wholly-rigid skeletons have been designed and synthesized. These molecules were built by using 4,4’-bipyridin-1-ium or viologen as hydrophilic moieties and phenyl or biphenyl as hydrophobic segments, bridged by a pyridazine unit. Their self-assembly behavior has been investigated by scanning electron microscopy (SEM), atomic force microscopy (AFM) and transmission electron microscopy (TEM), which revealed they could self-assemble into well-ordered nanoarchitectures with various morphologies such as vesicles, micro/nanorods and nanotubes in water or methanol, depending on their hydrophilic/hydrophobic fraction ratios.

Synthesis, antituberculostatic, antifungal and antibacterial activities of 3-substituted phenyl-6-substituted phenyl-1,2,4-triazolo[4,3-b]pyridazines

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NOVEL USE OF TRICYCLIC COMPOUND

Pharmaceutical compositions for enhancing the expression of apoAI are provided, which are used as medicaments for treatment of cardiovascular diseases on the basis of improving the functions of HDL.Pharmaceutical compositions for enhancing the expression of apoAI which comprises a compound of formula (I): in which X1 and X2 are independently an aryl or heteroaryl that may be optionally substituted, a hydrogen, a halogen, or the like; ring A is a benzene ring or 6-membered aromatic heterocyclic ring containing 1 to 3 N atoms that may be optionally condensed with another aromatic ring; R1 to R4 are independently a hydrogen, a halogen, a lower alkyl, a lower alkoxy or the like; a prodrug thereof, a pharmaceutically acceptable salt or solvate of them are disclosed.