37819-89-9

Basic information

• Product Name: Benzamide, N-(2,2,6,6-tetramethyl-4-piperidinyl)-
• Synonyms: N-(2,2,6,6-tetramethyl-piperidin-4-yl)-benzamide;4-benzoylamido-2,2,6,6-tetramethyl-piperidine;N-[2,2,6,6-tetramethyl-4-piperidinyl]benzamide;4-benzoylamino-2,2,6,6-tetramethyl piperidine
• CAS NO: 37819-89-9
• Molecular Formula: C16H24N2O
• Molecular Weight: 260.379
• Mol File: 37819-89-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 412.9±38.0 °C(Predicted)
• Density: 1.04±0.1 g/cm3(Predicted)
• CAS DataBase Reference: Benzamide, N-(2,2,6,6-tetramethyl-4-piperidinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-(2,2,6,6-tetramethyl-4-piperidinyl)-(37819-89-9)
• EPA Substance Registry System: Benzamide, N-(2,2,6,6-tetramethyl-4-piperidinyl)-(37819-89-9)

Safety Data

• Hazardous Substances Data: 37819-89-9(Hazardous Substances Data)

Upstream product

• 36768-62-4 4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE 
• 98-88-4 benzoyl chloride 
• 113230-84-5 N-(1-oxo-2,2,6,6-tetramethylpiperidin-4-yl)-benzoylamide 
• 591-50-4 iodobenzene 
• 201230-82-2 carbon monoxide 
• 14691-88-4 4-amino-2,2,6,6-tetramethyl-1-piperidine-1-oxyl 

Downstream Products

• 113230-84-5 N-(1-oxo-2,2,6,6-tetramethylpiperidin-4-yl)-benzoylamide 
• 63206-88-2 4-benzoylamino-2,2,6,6-tetramethyl-piperidine-1-carbonitrile 

Relevant articles and documents

4-Amino-TEMPO as N-Nucleophile in Palladium-Catalyzed Aminocarbonylation

Palladium-catalyzed aminocarbonylation of iodobenzene and iodoalkenes (1-iodocyclohexene, 4-tert-butyl-1-iodocyclohexene, α-iodostyrene, 17-iodoandrost-16-ene) was carried out using a free radical (4-amino-TEMPO) for the first time. Its reduced form (4-amino-2,2,6,6-tetramethylpiperidine) was also used as N-nucleophile. The free radical was partially reduced under aminocarbonylation conditions; however, the isolation of carbonylated products bearing a stable radical moiety was successfully accomplished. It was proved that the reduction of the 1-oxyl functionality took place to higher extent when more severe conditions (40 bar CO pressure) were used. The mixture of carboxamide and 2-ketocarboxamide products was obtained using iodobenzene because of single and double carbon monoxide insertion, respectively. In turn, carboxamide derivatives were formed exclusively when iodoalkenes were used as substrates.

Visual detection of formaldehyde by highly selective fluorophore labeling via gold(iii) complex-mediated three-component coupling reaction

A novel method for visual detection of formaldehyde with excellent selectivity via a gold(iii) complex-mediated three-component coupling reaction of resin-linked sterically bulky amines and fluorescent alkynes has been developed.

Photolabile protecting groups for nitroxide spin labels

Nitroxide spin labels can be protected against critical conditions of DNA/RNA or peptide synthesis by reduction and alkylation with light-sensitive groups such as nitrobenzyl- or aminocoumarins. High chemical stability qualifies tetraethylisoindoline 5 an