3789-85-3

Basic information

• Product Name: TRIMETHYLSILYL TRIMETHYLSILOXY SALICYLATE
• Synonyms: TRIMETHYLSILYL TRIMETHYLSILOXY SALICYLATE;BENZOICACID,2-[(TRIMETHYLSILYL)OX;2-[(Trimethylsilyl)oxy]benzoic acid trimethylsilyl ester;2-Trimethylsilyloxybenzoic acid trimethylsilyl ester;Trimethylsilyl 2-[(Trimethylsilyl)Oxy]Benzoate
• CAS NO: 3789-85-3
• Molecular Formula: C₁₃H₂₂O₃Si₂
• Molecular Weight: 298.48238
• Mol File: 3789-85-3.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: TRIMETHYLSILYL TRIMETHYLSILOXY SALICYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TRIMETHYLSILYL TRIMETHYLSILOXY SALICYLATE(3789-85-3)
• EPA Substance Registry System: TRIMETHYLSILYL TRIMETHYLSILOXY SALICYLATE(3789-85-3)

Safety Data

• Hazardous Substances Data: 3789-85-3(Hazardous Substances Data)

Usage

General Description

TRIMETHYLSILYL TRIMETHYLSILOXY SALICYLATE, also known as silicic acid, is an organic compound commonly used in the cosmetic and personal care industry as a sunscreen and UV filter. It is a clear, colorless liquid that is insoluble in water and has a low volatility. It works by absorbing and reflecting UV rays to provide protection against sun damage and premature aging of the skin. As a trimethylsilyl ester of salicylic acid, this chemical is also known for its soothing and anti-inflammatory properties, making it a popular ingredient in skincare products designed for sensitive or sun-exposed skin. However, like all chemical sunscreens, it is important to use TRIMETHYLSILYL TRIMETHYLSILOXY SALICYLATE responsibly and in conjunction with other sun protection measures to minimize potential health and environmental risks.

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 69-72-7 salicylic acid 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 10416-59-8 N,O-bis-(trimethylsilyl)-acetamide 
• 25561-30-2 N,O-Bis(trimethylsilyl)trifluoroacetamide 
• 1450-14-2 1,1,1,2,2,2-hexamethyldisilane 
• 5674-98-6 <2-Hydroxy-benzoyloxy>-trimethyl-silan 
• 95-53-4 o-toluidine 

Downstream Products

• 81790-03-6 2-<(3,5-di-tert-butyl-4-hydroxyphenyl)(3,5-di-tert-butyl-4-oxocyclohexa-2,5-dienylidene)methyl>-phenol 
• 79302-18-4 2-(trimethylsiloxy)benzoyl chloride 
• 81769-91-7 1-<(3,5-di-tert-butyl-4-hydroxyphenyl)(3,5-di-tert-butyl-4-oxocyclohexa-2,5-dienylidene)methyl>-2-<(2,5-dihydro-2,2,5,5-tetramethylpyrrol-1-yloxy-3-yl)(carbonyloxy)>benzene 
• 1341235-02-6 2-(5-methyl-2-phenyl-2H-1,2,3-diazaphosphol-4-yl)-4H-benzo[d]-1,3,2-dioxaphosphorin-4-one 
• 54049-02-4 2-methyl-2-vinyl-4H-benzo[d][1,3,2]dioxasilin-4-one 
• 18419-78-8 4H,4'H-2,2'-Spirobis[benzo[d][1,3,2]dioxasilin]-4,4'-dione 
• 75-77-4 chloro-trimethyl-silane 
• 1353581-83-5 2-(5-methyl-2-phenyl-2H-1,2,3-diazaphosphol-4-yl)-2,5-dioxo-4-trifluoromethyl-4-ethoxycarbonylbenzo[f]-1,3,2-dioxaphosphepine 
• 1353581-84-6 C₂₆H₂₂F₆N₂O₉P₂ 
• 1365236-98-1 2-(5-methyl-2-phenyl-2H-1,2,3-diazaphosphol-4-yl)-2,5-dioxo-4,4-bis(ethoxycarbonyl)benzo[f]-1,3,2-dioxaphosphepine 
• 1341235-05-9 2-(5-methyl-2-phenyl-2H-1,2,3-diazaphosphol-4-yl)-2,5-dioxo-4,4-bis(trifluoromethyl)benzo[f]-1,3,2-dioxaphosphepine 

Relevant articles and documents

Synthesis of trimethylsilyl carboxylates by HMDS under solvent-free conditions

A broad set of structurally different carboxylic acids were transformed into their trimethylsilyl esters with HMDS in a practically completely solvent-free process, while a catalytic amount of iodine was required in some cases. The process has several advantages over the known methods: untreated reactants, air atmosphere, mild and neutral conditions, no evolution of hydrogen halide, no need of an additional base, low amount of waste, completely without chromatography, low consumption of energy, and operational simplicity.

Gas-phase photocatalytic degradation and detoxification of o-toluidine: Degradation mechanism and Salmonella mutagenicity assessment of mixed gaseous intermediates

The photocatalytic degradation of toluidine over titanium oxide (TiO 2) thin films under UV irradiation was investigated. The degradation efficiency of 98.7% was obtained for a toluidine concentration of about 4500 μg L-1 and illumination of 240 min. The degradation intermediates produced during photocatalytic oxidation were identified using Fourier transform-infrared spectrometry (FTIR) and gas chromatography-mass spectrometry (GC-MS). Only a small amount of intermediates, including phenol and toluene, were found in the gas phase. Many other trace amount intermediates, such as 2-hydroxybenzaldehyde, 2-nitrobenzaldehyde, 2-hydroxybenzenemethanol, 2-hydroxybenzoic acid, phenol etc., were detected on the TiO2 surface. An Ames assay of the Salmonella typhimurium strains TA98 and TA100 was employed to evaluate the mutagenicity of toluidine and its gaseous photocatalytic degradation intermediates. With or without rat liver microsomal fraction (S9 mix) activation, neither toluidine nor its gaseous intermediates presented mutagenic activity against strains TA98 (±S9) and TA100 (-S9) at all tested doses. Toluidine, however, can induce a weak positive response to the TA100 strain with an S9 mix at doses as high as 4000 μg plate -1. An increase of revertants per plate was obtained after 30 min photocatalysis in the TA100 strain with S9 mix. As reaction time further increased, photocatalytic technology exhibited the ability to completely and efficiently detoxify toluidine. Both our chemical analysis and toxic evaluation indicate that all mutagenic intermediates in the gas can be completely eliminated within 240 min, which further suggests that photocatalytic technology is an effective approach for degrading aromatic amines.

Rapid gas chromatographic determination of serum salicylates after silylation

-