37895-46-8Relevant articles and documents
A Facile and Versatile Synthesis of Energetic Furazan-Functionalized 5-Nitroimino-1,2,4-Triazoles
Xu, Zhen,Cheng, Guangbin,Yang, Hongwei,Ju, Xuehai,Yin, Ping,Zhang, Jiaheng,Shreeve, Jean'ne M.
, p. 5877 - 5881 (2017)
An analogue-oriented synthetic route for the formulation of furazan-functionalized 5-nitroimino-1,2,4-triazoles has been explored. The process was found to be straightforward, high yielding, and highly efficient, and scalable. Nine compounds were synthesized and the physicochemical and energetic properties, including density, thermal stability, and sensitivity, were investigated, as well as the energetic performance (e.g., detonation velocities and detonation pressures) as evaluated by using EXPLO5 code. Among the new materials, compounds 4–6 and 11 possess high densities, acceptable sensitivities, and good detonation performances, and thereby demonstrate the potential applications as new secondary explosives.
Hybrid furoxanyl N-acylhydrazone derivatives as hits for the development of neglected diseases drug candidates
Hernandez, Paola,Rojas, Rosario,Gilman, Robert H.,Sauvain, Michel,Lima, Lidia M.,Barreiro, Eliezer J.,Gonzalez, Mercedes,Cerecetto, Hugo
, p. 64 - 74 (2013/03/13)
Neglected diseases represent a major health problem. It is estimated that one third of the world population is infected with tuberculosis and additionally Leishmaniosis and Chagas disease affect approximately 30 million people. N-Acylhydrazone moiety is a