37904-21-5

Basic information

• Product Name: 3-(4-NITRO-PHENYLCARBAMOYL)-ACRYLIC ACID
• Synonyms: ASISCHEM D13249;3-(4-NITRO-PHENYLCARBAMOYL)-ACRYLIC ACID;AKOS AUF0571;(2E)-4-[(4-nitrophenyl)amino]-4-oxobut-2-enoic acid;(E)-4-((4-nitrophenyl)amino)-4-oxobut-2-enoic acid;(E)-4-[(4-nitrophenyl)amino]-4-oxo-but-2-enoic acid;(E)-4-[(4-nitrophenyl)amino]-4-oxobut-2-enoic acid;(E)-4-keto-4-[(4-nitrophenyl)amino]but-2-enoic acid
• CAS NO: 37904-21-5
• Molecular Formula: C₁₀H₈N₂O₅
• Molecular Weight: 236.18
• Mol File: 37904-21-5.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(4-NITRO-PHENYLCARBAMOYL)-ACRYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-NITRO-PHENYLCARBAMOYL)-ACRYLIC ACID(37904-21-5)
• EPA Substance Registry System: 3-(4-NITRO-PHENYLCARBAMOYL)-ACRYLIC ACID(37904-21-5)

Safety Data

• Hazardous Substances Data: 37904-21-5(Hazardous Substances Data)

Upstream product

• 108-31-6 maleic anhydride 
• 100-01-6 4-nitro-aniline 
• 785-81-9 4-nitro-N-(phenylmethylene)benzenamine 
• 627-63-4 fumaryl dichloride 
• 2459-05-4 (E)-4-ethoxy-4-oxobut-2-enoic acid 

Downstream Products

• 4338-06-1 N-(4-nitrophenyl)maleimide 
• 37904-11-3 3-chloro-1-(4-nitrophenyl)pyrrolidine-2,5-dione 
• 59653-03-1 6β-[3-(4-nitro-phenylcarbamoyl)-acryloylamino]-penicillanic acid 
• 80167-59-5 (E)-3-(4-Nitro-phenylcarbamoyl)-acrylic acid methyl ester 
• 85142-47-8 (E)-3-(4-Nitro-phenylcarbamoyl)-acrylic acid ethyl ester 
• 1415110-25-6 tert-butyl 3-(4-nitrophenyl)-2,4-dioxo-3-azabicyclo[3.1.0]hexane-6-carboxylate 
• 1331786-73-2 ethyl 3-(4-nitrophenyl)-2,4-dioxo-3-azabicyclo[3.1.0]hexane-6-carboxylate 
• 1331751-70-2 ethyl 3-(4-nitrophenyl)-2,4-dioxo-3-azabicyclo[3.1.0]hexane-6-carboxylate 
• 1415110-31-4 diethyl 3-[(4-nitrophenyl)carbamoyl]cyclopropane-1,2-dicarboxylate 
• 1415110-33-6 diethyl 3-[(tert-butoxycarbonyl)(4-nitrophenyl)-carbamoyl]cyclopropane-1,2-dicarboxylate 

Relevant articles and documents

Synthesis, characterization crystal structures and DNA binding studies of zinc complexes with oxygen and nitrogen donor ligands

Three zinc metal complexes viz, [Zn(L1)2phen] (1), [Zn2(L2)4(bipy)2] (2) and [Zn(L2)2bipy·H2O] (3) where HL1 = 4-(o-toluidino)-4-oxobutanoic acid

Alizarin red S-TiO2-catalyzed cascade C(sp3)-H to C(sp2)-H bond formation/cyclization reactions toward tetrahydroquinoline derivatives under visible light irradiation

A very low amount of organic dye (Alizarin red S) sensitized TiO2 and it was successfully used to catalyze cascade C(sp3)-H to C(sp2)-H bond formation/cyclization reactions under visible light irradiation. The modified TiO2 photocatalyst efficiently, for the first time, advanced [4+2] cyclization of N,N-dimethylanilines and maleimides to the corresponding tetrahydroquinolines in air atmosphere. The reaction proceeds through α-amino radicals without additional oxidant at ambient temperature to afford products in good to excellent yields.

Graphene Oxide as a Carbocatalyst for a Diels–Alder Reaction in an Aqueous Medium

The Diels–Alder (DA) reaction, a [4+2] cycloaddition reaction, is highly important in synthetic organic chemistry and is frequently used in the synthesis of natural products containing six-membered rings. Herein, we report an efficient protocol for the DA reaction between 9-hydroxymethylanthracene and N-substituted maleimides using two-dimensional graphene oxide (GO) as a heterogeneous carbocatalyst in an aqueous medium at room temperature. High yields, a wide substrate scope, low temperature, excellent functional group tolerance, atom economy, and water as a green solvent are noteworthy features of this protocol. The heterogeneous GO catalyst can be easily recovered and used multiple times without any significant loss in catalytic activity.